Systems, devices, and methods including infection-fighting and monitoring shunts
2 Assignments
0 Petitions
Accused Products
Abstract
Systems, devices, methods, and compositions are described for providing an actively controllable shunt configured to, for example, monitor, treat, or prevent an infection.
89 Citations
472 Claims
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1-363. -363. (canceled)
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364. An implantable shunt system, comprising:
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a body structure having an outer surface and an inner surface defining one or more fluid-flow passageways configured to receive a cerebrospinal fluid of a biological subject; one or more energy emitters configured to emit an energy stimulus to one or more regions proximate at least one of the outer surface and the inner surface of the body structure, the energy stimulus of a character and for a duration sufficient to induce programmed cell death without substantially inducing necrosis of at least a portion of cells proximate at least one of the outer surface and the inner surface of the body structure; and a sensor component in optical communication along an optical path with at least one of the one or more energy emitters. - View Dependent Claims (368, 369, 372, 375, 379, 380, 386, 395, 396, 398, 413, 422, 429, 431, 441, 444)
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365-367. -367. (canceled)
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370. (canceled)
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371. (canceled)
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373. (canceled)
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374. (canceled)
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376-378. -378. (canceled)
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381-385. -385. (canceled)
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387-394. -394. (canceled)
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397. (canceled)
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399-412. -412. (canceled)
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414-421. -421. (canceled)
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423-428. -428. (canceled)
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430. (canceled)
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432-440. -440. (canceled)
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442. (canceled)
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443. (canceled)
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445. A method, comprising:
selectively energizing one or more regions of at least one fluid-flow passageway of an in vivo implanted cerebrospinal fluid management system in response to an automatically detected optical parameter associated with a cerebrospinal fluid received within the at least one fluid-flow passageway. - View Dependent Claims (446, 448, 449)
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447. (canceled)
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450. A method, comprising:
providing an energy stimulus to an interior of one or more fluid-flow passageways of an in vivo implanted cerebrospinal fluid management device in response to a change in an optical parameter associated with a cerebrospinal fluid received within the at least one fluid-flow passageway. - View Dependent Claims (451, 456, 457)
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452-455. -455. (canceled)
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458. (canceled)
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459. (canceled)
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460. A method, comprising:
delivering one or more energy stimuli to at least one of an interior and an exterior of one or more fluid-flow passageways of an indwelling cerebrospinal fluid management apparatus in response to an in vivo detected change in a refractive index parameter associated with a cerebrospinal fluid received within the one or more fluid-flow passageways. - View Dependent Claims (461, 462, 463)
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464. A method, comprising:
concurrently or sequentially delivering two or more energy stimuli to an interior and an exterior of one or more fluid-flow passageways of an indwelling cerebrospinal fluid management apparatus in response to a detected parameter associated with one or more of a cerebrospinal fluid received within the one or more fluid-flow passageways, a detected parameter associated with a tissue proximate an outer surface of the one or more fluid-flow passageways, and a physiological characteristic associated with a biological subject. - View Dependent Claims (466, 467)
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465. (canceled)
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468. A method, comprising:
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comparing, via integrated circuitry, one or more characteristics communicated from an implanted shunt device to stored reference data, the one or more characteristics including at least one of information associated with a cerebrospinal fluid received within one or more fluid-flow passageways of the implanted shunt device, information associated with a tissue proximate an outer surface of the implanted shunt device, and information associated with a physiological characteristic of the biological subject; and initiating a treatment protocol based at least in part on the comparison. - View Dependent Claims (469, 470, 471)
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472-754. -754. (canceled)
Specification