SYSTEMS AND METHODS FOR REPLACING SIGNAL ARTIFACTS IN A GLUCOSE SENSOR DATA STREAM
First Claim
1. A method for processing data from a glucose sensor, the method comprising:
- applying a voltage to an electrode, wherein the electrode is configured for measurement of a glucose concentration; and
detecting a signal artifact based on a signal response of the electrode to the applied voltage, wherein detecting a signal artifact comprises determining at least one condition selected from the group consisting of ischemia, a pH change, a temperature change, a change in available electrode surface area, and an interfering species.
1 Assignment
0 Petitions
Accused Products
Abstract
Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.
470 Citations
12 Claims
-
1. A method for processing data from a glucose sensor, the method comprising:
-
applying a voltage to an electrode, wherein the electrode is configured for measurement of a glucose concentration; and detecting a signal artifact based on a signal response of the electrode to the applied voltage, wherein detecting a signal artifact comprises determining at least one condition selected from the group consisting of ischemia, a pH change, a temperature change, a change in available electrode surface area, and an interfering species. - View Dependent Claims (2, 3, 4, 5, 6)
-
-
7. A system for processing data from a glucose sensor, the system comprising:
-
a glucose sensor comprising a working electrode, wherein the glucose sensor is configured to measure a glucose concentration; and electronic circuitry configured to apply a voltage to the working electrode and to measure a signal response of the working electrode to the applied voltage, wherein the electronic circuitry is configured to detect at least one condition based on the signal response, wherein the condition is selected from the group consisting of ischemia, a pH change, a temperature change, a change in available electrode surface area, and an interfering species. - View Dependent Claims (8, 9, 10, 11)
-
-
12. A method for detecting a signal artifact associated with a glucose sensor, the method comprising:
-
applying a voltage to a working electrode of a glucose sensor and measuring a signal response of the working electrode; and detecting a temperature or a change in temperature based on the signal response, wherein the temperature or the change in temperature is indicative of a signal artifact.
-
Specification