Systems, devices, and methods including infection-fighting and monitoring shunts
2 Assignments
0 Petitions
Accused Products
Abstract
Systems, devices, methods, and compositions are described for providing an actively controllable shunt configured to, for example, monitor, treat, or prevent an infection.
107 Citations
754 Claims
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1-725. -725. (canceled)
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726. An implantable shunt system, comprising:
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a body structure having a surface defining one or more fluid-flow passageways configured to receive a biological fluid of a biological subject; and one or more energy emitters configured to emit a pulsed thermal sterilizing stimulus of a character and for a time sufficient to induce apoptosis without substantially inducing necrosis of at least a portion of cells within the biological fluid proximate the surface of the body structure in response to a determination that an infectious agent is present within the biological fluid. - View Dependent Claims (727, 728, 729, 730, 731, 732, 733, 734, 735, 736, 737, 738, 739)
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740. A method of inhibiting a microbial colonization in the cerebrospinal fluid of a biological subject, comprising:
selectively energizing one or more regions of at least one cerebrospinal fluid-flow passageway of an indwelling implant via one or more pulsed thermal stimuli emitting components in response to an automatically detected optical density parameter associated with a cerebrospinal fluid received within the at least one cerebrospinal fluid-flow passageway. - View Dependent Claims (741, 742, 743)
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744. A method, comprising:
providing a pulsed thermal sterilizing stimulus to an interior of at least one cerebrospinal fluid-flow passageway of an implanted device in response to a change in a refractive index parameter indicative of a presence of an infectious agent within the at least one cerebrospinal fluid-flow passageway of the implanted device. - View Dependent Claims (745, 746, 747, 748, 749, 750, 751)
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752. A method, comprising:
delivering one or more pulsed thermal stimuli to at least one of an interior or an exterior of a cerebrospinal fluid-flow passageway of an indwelling implant apparatus in response to an in vivo detected change in a refractive parameter indicative of a presence of an infectious agent proximate the exterior or the interior of the cerebrospinal fluid-flow passageway. - View Dependent Claims (753)
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754. A method, comprising:
concurrently or sequentially delivering two or more energy stimuli to an interior surface and an exterior surface of a body structure of an indwelling apparatus in response to a detected parameter associated with one or more of a cerebrospinal fluid received within the interior of the body structure, a detected parameter associated with a tissue proximate the exterior surface, and a physiological characteristic associated with a biological subject.
Specification