POROUS FIBER ELECTRODE COATING AND RELATED METHODS
First Claim
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1. A medical electrical lead comprising:
- a flexible, elongated polymeric lead body defining at least one longitudinal lumen therethrough;
a conducting wire extending through the at least one lumen;
a connector coupled to the lead body for mechanically and electrically coupling the lead to an implantable pulse generator device;
an electrode disposed on an exterior portion of the lead body, wherein the electrode is electrically coupled to the conducting wire; and
a porous coating disposed on the electrode, the porous coating comprising;
a polymeric nanofiber mesh comprising polyetheretherketone;
a first coating disposed on the fiber mesh, comprising TiO2 and polyacrylic acid; and
a second coating disposed on the first coating, comprising a fluoroalkylsilane.
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Abstract
The embodiments herein relate to an electrode having a porous coating including a fiber mesh, a multi-layer coating, and an outer coating, and a method of making the same. The various electrode coating embodiments include pores in the coating that prevent access by protein or cells while allowing for ion and/or liquid access.
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Citations
23 Claims
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1. A medical electrical lead comprising:
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a flexible, elongated polymeric lead body defining at least one longitudinal lumen therethrough; a conducting wire extending through the at least one lumen; a connector coupled to the lead body for mechanically and electrically coupling the lead to an implantable pulse generator device; an electrode disposed on an exterior portion of the lead body, wherein the electrode is electrically coupled to the conducting wire; and a porous coating disposed on the electrode, the porous coating comprising; a polymeric nanofiber mesh comprising polyetheretherketone; a first coating disposed on the fiber mesh, comprising TiO2 and polyacrylic acid; and a second coating disposed on the first coating, comprising a fluoroalkylsilane. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A medical electrical lead comprising:
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a flexible, elongated polymeric lead body defining at least one longitudinal lumen therethrough; a conducting wire extending through the at least one lumen; a connector coupled to the lead body for mechanically and electrically coupling the lead to an implantable pulse generator device; an electrode disposed on an exterior portion of the lead body, wherein the electrode is electrically coupled to the conducting wire; and a porous coating disposed on the electrode, the porous coating comprising; a patterned fiber mesh comprising polytetrafluoroethylene; and a first coating disposed on the fiber mesh, the first coating comprising a hydrophilic composition. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16)
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17. A method of making an electrode for a medical electrical lead of the type having a lead body and at least one electrical conducting wire therein, the method comprising:
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forming an electrode on the lead body; disposing a polymeric nanofiber mesh on the electrode, the nanofiber mesh comprising polyetheretherketone; applying a first multi-layer coating to the polymeric nanofiber mesh, the first multi-layer coating comprising layers of TiO2 and polyacrylic acid; and applying a second coating to the first multi-layer coating, the second coating comprising fluoroalkylsilane. - View Dependent Claims (18, 19, 20)
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21. A method of making an electrode for a medical electrical lead of the type having a lead body and at least one electrical conducting wire therein, the method comprising:
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forming an electrode on the lead body; disposing a patterned fiber mesh on the electrode, the patterned fiber mesh comprising polytetrafluoroethylene; and applying a first coating to the patterned fiber mesh, the first coating comprising a hydrophilic composition. - View Dependent Claims (22, 23)
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Specification