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AMELIORATION OF HETEROPHILE ANTIBODY IMMUNOSENSOR INTERFERENCE

  • US 20100248273A1
  • Filed: 03/25/2009
  • Published: 09/30/2010
  • Est. Priority Date: 03/25/2009
  • Status: Active Grant
First Claim
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1. A method of reducing interference from heterophile antibodies in an analyte immunoassay, comprising:

  • (a) amending a whole blood sample with non-human IgM or fragments thereof by dissolving into said sample a dry reagent to yield a non-human IgM concentration of at least 20 μ

    g/mL or equivalent fragment concentration; and

    (b) performing an electrochemical immunoassay on the amended sample to determine the concentration of said analyte in said sample.

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