IONIC SILICONE HYDROGELS HAVING IMPROVED HYDROLYTIC STABILITY
First Claim
1. A polymer formed from reactive components comprising at least one silicone component comprising at least one trimethylsiloxy silyl group and at least one ionic component comprising at least one anionic group wherein said silicone component and said ionic component are present in said polymer in molar concentrations providing a stability product less than about 0.002.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention relates to ionic silicone hydrogel polymers displaying improved thermal stability. More specifically, the present invention relates to a polymer formed from reactive components comprising at least one silicone component and at least one ionic component comprising at least one anionic group. The polymers of the present invention display good thermal stability and desirable protein uptake.
-
Citations
52 Claims
- 1. A polymer formed from reactive components comprising at least one silicone component comprising at least one trimethylsiloxy silyl group and at least one ionic component comprising at least one anionic group wherein said silicone component and said ionic component are present in said polymer in molar concentrations providing a stability product less than about 0.002.
-
11. A polymer formed from reactive components comprising about 0.1 to about 0.9 weight % of at least one anionic component and at least one silicone component selected from the group consisting of reactive polydialkylsiloxane selected from compounds of Formula I:
-
12. A contact lens formed by polymerizing components comprising at least one silicone component and at least one ionic component wherein said ionic component is present in said polymer in concentration less than 0.8 wt % and wherein said contact lens absorbs at least about 10 μ
- g lysozyme, less than about 5 μ
g lipocalin and wherein at least about 50% of all proteins absorbed in or on said contact lens are in native form. - View Dependent Claims (13, 14, 17, 18, 19, 20, 21, 22, 23, 25, 26, 29, 30, 31, 32)
- g lysozyme, less than about 5 μ
-
33. A contact lens formed by polymerizing components comprising at least one silicone component and at least one ionic component comprising at least one carboxylic acid group in molar concentrations up to about 9.3 mmol/100 gm and wherein said contact lens absorbs at least about 10 μ
- g lysozyme, less than about 5 μ
g lipocalin and wherein at least about 50% of proteins absorbed in or on said contact lens are in native form. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52)
- g lysozyme, less than about 5 μ
Specification