SYSTEM AND METHOD FOR MONITORING CARDIOPULMONARY FLUID TRANSFER RATES USING AN IMPLANTABLE MEDICAL DEVICE
First Claim
1. A method for use with an implantable medical device for implant within a patient, the method comprising:
- determining a cardiopulmonary fluid transfer rate within the patient, wherein the cardiopulmonary fluid transfer rate includes at least one of a fluid transfer rate from heart-to-lung and a fluid transfer rate from lung-to-lymphatic system; and
controlling at least one device function in response to the cardiopulmonary fluid transfer rate.
1 Assignment
0 Petitions
Accused Products
Abstract
Techniques are provided for use by a pacemaker or other implantable medical device for detecting and tracking trends in cardiopulmonary fluid transfer rates—such as heart-to-lung fluid perfusion rates and lung-to-lymphatic system fluid excretion rates—and for detecting heart failure, dyspnea or other cardiopulmonary conditions. In one example, the device periodically measures transthoracic admittance values. A first exponential time-constant (k1) is determined using curve-fitting from admittance values obtained while the patient is in a sleep posture. Time-constant k1 is representative of the fluid perfusion rate. A second exponential time-constant (k2) is determined based on admittance values obtained while the patient is standing/walking/sitting. The second exponential time-constant (k2) is representative of the fluid excretion rate from the lungs. The device then detects trends, if any, in the time-constants (or in “DC” baseline values) to detect or predict medical conditions such as an imminent heart failure exacerbation.
-
Citations
34 Claims
-
1. A method for use with an implantable medical device for implant within a patient, the method comprising:
-
determining a cardiopulmonary fluid transfer rate within the patient, wherein the cardiopulmonary fluid transfer rate includes at least one of a fluid transfer rate from heart-to-lung and a fluid transfer rate from lung-to-lymphatic system; and controlling at least one device function in response to the cardiopulmonary fluid transfer rate. - View Dependent Claims (2, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
-
-
3. The method of claim 3 wherein determining the fluid perfusion transfer rate includes:
-
measuring values representative of electrical admittance through at least a portion of the lungs; identifying a first set of values measured while the patient is in a sleep posture; determining a first exponential time-constant (k1) based on the first set of values; and equating the first exponential time-constant (k1) with the rate of transfer of fluids from heart-to-lung within the patient. - View Dependent Claims (4, 5, 6, 7, 8, 9, 10, 11)
-
-
28. A system for use with an implantable medical device for implant within a patient, the system comprising:
-
a cardiopulmonary fluid transfer rate determination system operative to determine at least one of a fluid transfer rate from heart-to-lung and a fluid transfer rate from lung-to-lymphatic system; and a cardiopulmonary fluid transfer rate-based controller operative to control at least one device function based on a cardiopulmonary fluid transfer rate. - View Dependent Claims (29, 30, 31, 32, 33)
-
-
34. A system for use with an implantable medical device for implant within a patient, the system comprising:
-
means for determining fluid transfer rates within the patient representative of at least one form of cardiopulmonary fluid transfer; and means for detecting an indication of heart failure within the patient based on the cardiopulmonary fluid transfer rate.
-
Specification