Neural Stimulation For Treatment of Metabolic Syndrome and Type 2 Diabetes
First Claim
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1. A method, of treating a type II diabetic patient comprising:
- selecting a patient suffering from type II diabetes;
electrically modulating a splanchnic nerve of the patient in a stimulation pattern that increases lean muscle mass as a percentage of body mass and moderates insulin levels;
wherein said stimulation pattern comprises a stimulation intensity, and said stimulation intensity is between 0.005 and 5.0 mA-msec;
wherein said stimulation pattern comprises an on time and an off time; and
wherein said off time is no less than said on time;
wherein said stimulation pattern comprises a duty cycle of about 50%;
wherein said stimulation pattern comprises a frequency, a pulse width, and a current; and
wherein said frequency is between 0.1 Hz and 50 Hz;
said pulse width is between 100 microseconds and 1 millisecond; and
said current is between 0.1 mA and 10 mA.
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Abstract
Systems and methods are described for treating metabolic syndrome and/or Type 2 diabetes, and/or one or more of their attendant conditions, by neural stimulation. In one embodiment, an implantable pulse generator is electrically coupled to a peripheral nerve, such as the splanchnic nerve. Neural stimulation configured to either block transmission or stimulate transmission of the peripheral nerve may be used to treat metabolic syndrome and Type 2 diabetes.
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Citations
14 Claims
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1. A method, of treating a type II diabetic patient comprising:
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selecting a patient suffering from type II diabetes; electrically modulating a splanchnic nerve of the patient in a stimulation pattern that increases lean muscle mass as a percentage of body mass and moderates insulin levels; wherein said stimulation pattern comprises a stimulation intensity, and said stimulation intensity is between 0.005 and 5.0 mA-msec; wherein said stimulation pattern comprises an on time and an off time; and
wherein said off time is no less than said on time;wherein said stimulation pattern comprises a duty cycle of about 50%; wherein said stimulation pattern comprises a frequency, a pulse width, and a current; and wherein said frequency is between 0.1 Hz and 50 Hz;
said pulse width is between 100 microseconds and 1 millisecond; and
said current is between 0.1 mA and 10 mA. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification