IMPLANTABLE APPARATUS FOR THE TREATMENT OF A SURFACE OF A DAMAGED VESSEL OR BODY CAVITY BY ELECTROMAGNETIC ENERGY

• US 20100249891A1
• Filed: 11/03/2009
• Published: 09/30/2010
• Est. Priority Date: 03/26/2009
• Status: Abandoned Application

• Current Assignee: Arista Therapeutics, Inc.
• Original Assignee: Arista Therapeutics, Inc.
• Inventors: O'FLYNN, DAVID, Appel, Roni, Derbin, J. Todd, Donaghy, Dymphna
• Application Number:
  US12/611,927
• Publication Number:
  US 20100249891A1
• Time in Patent Office: Days
• US Class Current: 607/92
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61N 2005/0645 Applicators worn by the patient
• CPC Class Codes: A61N 2005/0652 Arrays of diodes
• CPC Class Codes: A61N 5/0601 Apparatus for use inside the body

Abstract

The present invention provides an improved apparatus and method for the treatment of body cavities and damaged vessels using electromagnetic energy. A device and apparatus according to the invention may be used to irradiate a tissue surface internal to the body, for example, for treatment of an aneurysm, tissue reconstructing, or removal of an anomaly in a blood vessel. Light energy may be radiated from an implantable and retrievable biocompatible matrix into which is mounted a plurality of electromagnetic energy sources, such as light emitting diodes or the like.

Claims

1. An implantable apparatus for internal treatment of body cavities and damaged internal vessels using electromagnetic energy, comprising:

a biocompatible matrix including an adhesive for attaching the reinforced matrix to a tissue surface to be treated;

a plurality of electromagnetic energy sources mounted to said biocompatible matrix; and

a remote electrical source in electrical communication with said plurality of electromagnetic energy sources for activation and control of energy emitted by said electromagnetic energy sources.

2. The implantable apparatus of claim 1, wherein said adhesive is selected from the group consisting of surgical glue, a cyanoacrylate adhesive, bioglue, and a fibrin-type glue.

3. The implantable apparatus of claim 1, further comprising a reinforcing carrier backing attached to said biocompatible matrix.

4. The implantable apparatus of claim 3, wherein said reinforcing carrier backing comprises a reinforcing carrier sleeve.

5. The implantable apparatus of claim 3, wherein said matrix and reinforcing carrier backing in combination has circumferential rigidity.

6. The implantable apparatus of claim 1, wherein said biocompatible matrix is formed from a polymeric material.

7. The implantable apparatus of claim 6, wherein said polymeric material is selected from the group consisting of a porous, non-fabric substrate, PET fabric, porous PTFE, and porous expanded PTFE.

8. The implantable apparatus of claim 1, wherein said biocompatible matrix is formed from a material of biological origin.

9. The implantable apparatus of claim 8, wherein said material of biological origin is selected from the group consisting of material harvested or grown from bovine or human blood vessels.

10. The implantable apparatus of claim 1, wherein said biocompatible matrix is formed from a vascular graft material.

11. The implantable apparatus of claim 10, wherein said vascular graft material comprises a porous, non-fabric substrate.

12. The implantable apparatus of claim 1, wherein said plurality of electromagnetic energy sources comprise a plurality of light sources.

13. The implantable apparatus of claim 1, wherein said plurality of electromagnetic energy sources comprise a plurality of light emitting diodes embedded in said biocompatible matrix.

14. The implantable apparatus of claim 1, wherein said plurality of electromagnetic energy sources provide irradiation in the range of 500 to 2010 nm.

15. The implantable apparatus of claim 1, wherein said plurality of electromagnetic energy sources provide low level laser irradiation.

16. The implantable apparatus of claim 14, wherein said irradiation is in the range of 500 to 900 nm.

17. The implantable apparatus of claim 14, wherein said irradiation is in the range of 780 to 2010 nm.

18. The implantable apparatus of claim 14, wherein said irradiation is in the range of 600 to 900 nm.

19. The implantable apparatus of claim 14, wherein said irradiation has an energy flux in the range of about 0.01 to about 50 Joules/cm².

20. The implantable apparatus of claim 14, wherein said irradiation has an energy flux in the range of about 0.1 to about 5 Joules/cm².

21. The implantable apparatus of claim 1, wherein said remote electrical source comprises at least one electrical connection to the remote electrical source.

22. The implantable apparatus of claim 1, wherein said remote electrical source comprises a programmable energy supply to supply electrical energy to the electromagnetic energy sources.

23. The implantable apparatus of claim 1, wherein said remote electrical source comprises RF coupling means for transmitting electrical energy from the remote electrical source to an internal body cavity or vessel to be treated.

24. The implantable apparatus of claim 1, wherein said biocompatible matrix is placed on an external surface of an implantable placement substrate.

25. A method for the internal treatment of body cavities and damaged internal vessels using electromagnetic energy, comprising:

providing an illuminating device including a biocompatible matrix including an adhesive for attaching the reinforced matrix to a tissue surface to be treated, a plurality of electromagnetic energy sources mounted to said biocompatible matrix, and a remote electrical source in electrical communication with said plurality of electromagnetic energy sources for activation and control of energy emitted by said electromagnetic energy sources;

delivering the illuminating device to a body site to be treated;

applying the illuminating device to a tissue surface to be treated; and

irradiating the tissue surface;

26. The method of claim 25, wherein said step of delivering the illuminating device comprises introducing the illuminating device into a body cavity by an endoscopic procedure.

27. The method of claim 25, wherein said step of delivering the illuminating device comprises introducing the illuminating device into a body cavity by an endovascular placement system.

28. The method of claim 27, wherein said step of introducing the illuminating device into a body cavity by an endovascular placement system comprises mounting the illuminating device on an exterior surface of an endovascular placement system.

29. The method of claim 28, wherein said endovascular placement system comprises a stent.

30. The method of claim 28, further comprising the step of remotely controlling the remote electrical source by electrical connections to the remote electrical source.

31. The method of claim 28, further comprising the step of remotely controlling the remote electrical source by an RF coupling from an external source.

32. The method of claim 25, further comprising varying a radiation therapy.

33. The method of claim 25, further comprising varying a radiation frequency.

34. The method of claim 25, further comprising varying a surface treatment by time phasing of the energy from the light source.