PROSTHETIC HEART VALVE SYSTEM
First Claim
1. A prosthetic heart valve system comprising:
- a plastically-expandable base stent adapted to anchor against a heart valve annulus, the base stent being radially expandable from a compressed configuration to an expanded configuration, wherein at least a portion of the stent in the expanded configuration has a tri-lobular cross-sectional profile in a plane perpendicular to a longitudinal axis of the base stent.
1 Assignment
0 Petitions
Accused Products
Abstract
An exemplary two-stage prosthetic heart valve system has a radially expandable base stent implanted within a native valve annulus. The two-stage heart valve system also has a valve component that is delivered to and mounted within the base stent in a separate or sequential operation after the base stent has been anchored within the annulus. The valve component in certain embodiments comprises a hybrid valve component that includes a conventional, non-expandable surgical valve that is modified to include an expandable coupling stent that can be expanded to engage the inner surface of the base stent, thereby anchoring the valve component to the base stent. In its expanded configuration, the outflow end portion base stent has tri-lobular shape that closely conforms to the shape of the aortic root and a support ring of the prosthetic valve that is mounted within the base stent.
370 Citations
27 Claims
-
1. A prosthetic heart valve system comprising:
a plastically-expandable base stent adapted to anchor against a heart valve annulus, the base stent being radially expandable from a compressed configuration to an expanded configuration, wherein at least a portion of the stent in the expanded configuration has a tri-lobular cross-sectional profile in a plane perpendicular to a longitudinal axis of the base stent. - View Dependent Claims (2, 3, 4, 5, 6, 7)
-
8. A prosthetic heart valve system comprising:
-
a prosthetic valve comprising a support frame and valve leaflets supported by the support frame; and a radially-expandable base stent adapted to anchor against a heart valve annulus, the base stent being radially expandable from a compressed configuration for delivery to the annulus to an expanded configuration for receiving the prosthetic valve; wherein the base stent in the expanded configuration has an outflow end having a first diameter and an inflow end having a second diameter smaller that the first diameter, the base stent in the expanded configuration also comprising an outflow end portion that tapers down to an inflow end portion, at least a portion of the outflow end portion having a tri-lobular shape, the outflow end being sized to allow the prosthetic valve to be inserted into the base stent such that the support frame can be mounted within the outflow end portion. - View Dependent Claims (9, 10, 11, 12, 13, 14)
-
-
15. A prosthetic heart valve system comprising:
-
a delivery apparatus comprising an expansion device having an outer mounting surface; and a radially-expandable stent mounted in a radially compressed state on the mounting surface of the expansion device, the stent being adapted to anchor against a heart valve annulus; the expansion device being configured to expand radially outward from a first, compressed configuration to a second, expanded configuration to expand the stent to an expanded state, the mounting surface being shaped to cause at least a portion of the stent to assume a tri-lobular cross-sectional profile when expanded. - View Dependent Claims (16, 17, 18, 19, 20)
-
-
21. A method of implanting a prosthetic heart valve system, comprising:
-
advancing a base stent to an implant position adjacent a heart valve annulus; radially expanding the base stent so as to anchor the base stent to the heart valve annulus, the expanded base stent having an outflow end portion and an inflow end portion, at least a portion of the outflow end portion having a tri-lobular cross-sectional profile; providing a prosthetic valve having a non-expandable, non-collapsible ring and valve leaflets coupled to the ring; advancing the prosthetic valve into the outflow end portion of the base stent; and anchoring the prosthetic valve to the base stent. - View Dependent Claims (22, 23, 24, 25, 26, 27)
-
Specification