Method and System for Determining the Difference Between Pre-Prandial and Post-Prandial Blood Glucose Values

• US 20100250144A1
• Filed: 02/12/2010
• Published: 09/30/2010
• Est. Priority Date: 03/30/2009
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Blasberg, Peter, Kloos, Alfred, Koehler, Matthias
• Granted Patent: US 8,452,545 B2
• Time in Patent Office: Days
• US Class Current: 702/19
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

A method and system is disclosed that enables a less error-prone and preferably automatic assignment of pre-prandial and post-prandial blood glucose values associated with a meal to improve determining the difference between pre-prandial and post-prandial blood glucose measurements as follows. Blood glucose measurements are read and provided with a relative or absolute time mark and labeled as pre-prandial and reading out post-prandial blood glucose measurements provided with a relative or absolute time mark from the memory of a blood glucose measuring instrument. The chronological sequence of the blood glucose measurements labeled as pre-prandial are determined. The post-prandial blood glucose measurements that correspond to each of the pre-prandial blood glucose measurements are determined by applying a time selection criterion. The difference between corresponding pre-prandial and post-prandial blood glucose measurements is determined. The difference values are displayed that have improved diagnostic value.

Claims

1. A method for determining the difference between pre-prandial and post-prandial blood glucose measurements, comprising the steps:

i) reading out blood glucose measurements provided with a relative or absolute time mark and labelled as pre-prandial and reading out post-prandial blood glucose measurements provided with a relative or absolute time mark from the memory of a blood glucose measuring instrument;

ii) determining the chronological sequence of the blood glucose measurements labelled as pre-prandial;

iii) determining the post-prandial blood glucose measurements that correspond to each of the pre-prandial blood glucose measurements by applying a time selection criterion;

iv) determining the difference between corresponding pre-prandial and post-prandial blood glucose measurements; and

v) displaying the difference values.

2. The method according to claim 1, wherein

allocating to time categories which represent meals the blood glucose measurements and the difference between corresponding pre-prandial and post-prandial blood glucose measurements.

3. The method according to claim 2, wherein

the allocation to the time categories is based on the time of the pre-prandial blood glucose measurement.

4. The method according to claim 1, wherein

the sorting in step ii) is carried out in ascending order starting with the oldest pre-prandial blood glucose measurement.

5. The method according to claim 1, wherein

a time frame of at least 60 minutes and at most 140 minutes after the respective pre-prandial blood glucose measurement is used in step iii) as a time selection criterion.

6. The method according to claim 1, wherein

if several post-prandial blood glucose measurements are present which fulfil the time selection criterion, the highest blood glucose measurement is used in each case in step iv).

7. The method according to claim 1, wherein

steps ii) and iii) proceed in such a manner that

starting with the oldest pre-prandial blood glucose measurement firstly the highest corresponding post-prandial blood glucose measurement is determined;

storing this oldest blood glucose measurement pair for further processing;

determining subsequently the next oldest pre-prandial blood glucose measurement and the highest corresponding post-prandial blood glucose measurement;

storing this next oldest blood glucose measurement pair for further processing; and

repeating these steps until all blood glucose measurements have been taken into consideration up to the most recent pre-prandial blood glucose measurement and, optionally, the highest corresponding post-prandial blood glucose measurement.

8. A system for determining the difference between pre-prandial and post-prandial blood glucose measurements, comprising:

a data processing device, and

a computer program for carrying out the method.

9. A computer program product for determining the difference between pre-prandial and post-prandial blood glucose measurements, comprising:

a computer program for carrying out the method.