METHODS, SYSTEMS AND DEVICES FOR NON-INVASIVE OPEN VENTILATION WITH GAS DELIVERY NOZZLES WITHIN NASAL PILLOWS

• US 20100252037A1
• Filed: 04/02/2010
• Published: 10/07/2010
• Est. Priority Date: 04/02/2009
• Status: Active Grant

• Current Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Original Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Inventors: Cipollone, Joseph, Eghbal, Darius, Aguirre, Joey, Allum, Todd, Wondka, Anthony D., Kapust, Gregory, Gerber, Anthony
• Granted Patent: US 10,695,519 B2
• Time in Patent Office: Days
• US Class Current: 128/203.120
• CPC Class Codes: A61M 16/0003 Accessories therefor, e.g. sensors, vibrators, negative pressure
• CPC Class Codes: A61M 16/0006 with means for creating vibrations in patients' airways
• CPC Class Codes: A61M 16/0057 Pumps therefor
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/0096 High frequency jet ventilation
• CPC Class Codes: A61M 16/0493 with means for protecting the tube from damage caused by the patient's teeth, e.g. bite block
• CPC Class Codes: A61M 16/0605 Means for improving the adaptation of the mask to the patient
• CPC Class Codes: A61M 16/0622 having an underlying cushion
• CPC Class Codes: A61M 16/0666 Nasal cannulas or tubing devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02
• CPC Class Codes: A61M 16/0677 Gas-saving devices therefor
• CPC Class Codes: A61M 16/0683 Holding devices therefor
• CPC Class Codes: A61M 16/0688 by means of an adhesive
• CPC Class Codes: A61M 16/0825 with ball-sockets
• CPC Class Codes: A61M 16/0841 for sampling
• CPC Class Codes: A61M 16/0858 Pressure sampling ports
• CPC Class Codes: A61M 16/0875 Connecting tubes
• CPC Class Codes: A61M 16/0883 Circuit type
• CPC Class Codes: A61M 16/101 using an oxygen concentrator
• CPC Class Codes: A61M 16/107 in the inspiratory path
• CPC Class Codes: A61M 16/127 : by Venturi effect, i.e. entrainment mixers
• CPC Class Codes: A61M 16/16 : Devices to humidify the respiration air A61M16/1045 takes precedence
• CPC Class Codes: A61M 16/201 : Controlled valves
• CPC Class Codes: A61M 16/208 : Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
• CPC Class Codes: A61M 2016/0015 : inhalation detectors
• CPC Class Codes: A61M 2016/0021 : with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0024 : with an on-off output signal, e.g. from a switch
• CPC Class Codes: A61M 2016/0027 : pressure meter
• CPC Class Codes: A61M 2016/0036 : in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2016/0661 : with customised shape
• CPC Class Codes: A61M 2202/0007 : introduced into the body
• CPC Class Codes: A61M 2202/0208 : Oxygen
• CPC Class Codes: A61M 2202/03 : Gases in liquid phase, e.g. cryogenic liquids
• CPC Class Codes: A61M 2205/0205 : Materials having antiseptic or antimicrobial properties, e.g. silver compounds, rubber with sterilising agent
• CPC Class Codes: A61M 2205/17 : with redundant control systems
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/8206 : battery-operated
• CPC Class Codes: A61M 2230/40 : Respiratory characteristics

Abstract

A non-invasive ventilation system may include a nasal interface. The nasal interface may include a left outer tube with a left distal end adapted to impinge a left nostril, at least one left opening in the left distal end in pneumatic communication with the left nostril, and a left proximal end of the left outer tube in fluid communication with ambient air. The left proximal end of the left outer tube may curve laterally away from a midline of a face. A right outer tube may be similarly provided. One or more left jet nozzles may direct ventilation gas into the left outer tube, and one or more right jet nozzles may direct ventilation gas into the right outer tube. The jet nozzles may be in fluid communication with the pressurized gas supply.

Claims

1. A non-invasive ventilation system comprising:

a nasal interface comprising a left outer tube comprising a left distal end adapted to impinge a left nostril, at least one left opening in the left distal end in pneumatic communication with the left nostril, a left proximal end of the left outer tube in fluid communication with ambient air, and wherein the left proximal end of the left outer tube curves laterally away from a midline of a face;

a right outer tube comprising a right distal end adapted to impinge a right nostril, at least one right opening in the right distal end in pneumatic communication with the right nostril, a right proximal end of the right outer tube in fluid communication with ambient air, and wherein the right proximal end of the right outer tube curves laterally away from the midline of the face;

one or more left jet nozzles for directing ventilation gas into the left outer tube, wherein the one or more left jet nozzles are in fluid communication with the pressurized gas supply; and

one or more right jet nozzles for directing ventilation gas into the right outer tube, wherein the one or more right jet nozzles are in fluid communication with the pressurized gas supply.

2. The system of claim 1, wherein the one or more left jet nozzles, the one or more right jet nozzles, or both are directed toward an inner wall of the left outer tube, the right outer tube, or both.

3. The system of claim 1, wherein the left outer tube and the right outer tube comprise a jet pump throat and a jet pump diffuser.

4. The system of claim 1, wherein the one or more left jet nozzles are flush with an entrance of the left outer tube and the one or more right jet nozzles are flush with an entrance of the right outer tube.

5. The system of claim 1, wherein the one or more left jet nozzles are within an entrance of the left outer tube and the one or more right jet nozzles are within an entrance of the right outer tube.

6. The system of claim 1, wherein the one or more left jet nozzles are outside an entrance of the left outer tube and the one or more right jet nozzles are outside an entrance of the right outer tube.

7. The system of claim 1, further comprising at least one sensing lumen.

8. The system of claim 7, further comprising at least one secondary sensing lumen.

9. The system of claim 1, further comprising a drug delivery lumen.

10. The system of claim 1, further comprising a humidity delivery lumen.

11. The system of claim 1, further comprising a coupler between the left outer tube and the right outer tube.

12. The system of claim 1, wherein the left outer tube swivels relative to the right outer tube.

13. The system of claim 1, further comprising a ventilator for delivering ventilation gas in synchrony with phases of breathing.

14. The system of claim 1, wherein ambient air is entrained through the outer tube.

15. The system of claim 14, wherein the ventilation gas and the entrained ambient air elevates lung pressure, elevates lung volume, decreases work of breathing or increases airway pressure.

16. The system of claim 1, wherein the left outer tube and the right outer tube are stabilized against a face.

17. The system of claim 1, further comprising a wearable ventilator and a portable gas supply.

18. The system of claim 1, further comprising a ventilator, the ventilator comprising a control unit, and wherein the control unit adjusts an output of the ventilator to match a patient'"'"'s needs based on information from at least one sensor.

19. The system of claim 1, further comprising a ventilator, the ventilator comprising a control unit, the control unit comprising a speaking mode sensing system, and wherein the control unit adjusts an output of the ventilator while the patient is speaking to not be asynchronous with a patient'"'"'s spontaneous breathing.

20. The system of claim 1, further comprising a ventilator, the ventilator comprising a control unit, the control unit comprising an apnea or hypopnea sensing system, and wherein the control unit adjusts an output of the ventilator based on apnea or hypopnea.

21. The system of claim 1, wherein the left outer tube or the right outer tube comprises sound reduction features selected from the group of:

a secondary aperture, a filter for the aperture, textured surfaces, a muffler, sound absorbing materials, an angled jet nozzle, non-concentric jet nozzle positions, and combinations thereof.

22. A non-invasive ventilation system comprising:

a ventilator;

a gas delivery circuit comprising a left gas path and a right gas path; and

a nasal interface comprising a left outer tube receiving ventilation gas from at least one nozzle on a distal end of the left gas path and a right outer tube receiving ventilation gas from at least one nozzle on a distal end of the right gas path;

wherein the left outer tube and the right outer tube curve laterally away from a midline of a nose.

23. The system of claim 22, wherein ventilation gas is directed toward an inner wall of the left outer tube and the right outer tube.

24. The system of claim 22, wherein the at least one nozzle on the distal end of the left gas path is within the left outer tube and the at least one nozzle on the distal end of the right gas path is within the right outer tube.

25. The system of claim 22, wherein the at least one nozzle on the distal end of the left gas path is flush with the left outer tube and the at least one nozzle on the distal end of the right gas path is flush with the right outer tube.

26. The system of claim 22, wherein the at least one nozzle on the distal end of the left gas path is outside the left outer tube and the at least one nozzle on the distal end of the right gas path is outside the right outer tube.

27. The system of claim 22, wherein the left gas path and the right gas path are stabilized against a face.

28. The system of claim 22, further comprising a portable gas supply, and wherein the ventilator is portable.

29. The system of claim 22, wherein the ventilator comprises a control unit, and wherein the control unit adjusts an output of the ventilator to match a patient'"'"'s needs based on information from at least one sensor.

30. The system of claim 22, wherein the ventilator comprises a control unit, the control unit comprising a speaking mode sensing system, and wherein the control unit adjusts an output of the ventilator while the patient is speaking to not be asynchronous with a patient'"'"'s spontaneous breathing.

31. The system of claim 22, wherein the ventilator comprises a control unit, the control unit comprising an apnea or hypopnea sensing system, and wherein the control unit adjusts an output of the ventilator based on apnea or hypopnea.

32. The system of claim 22, wherein the left gas path or the right gas path comprises sound reduction features selected from the group of:

a secondary aperture, a filter for the aperture, textured surfaces, a muffler, sound absorbing materials, an angled jet nozzle, non-concentric jet nozzle positions, and combinations thereof.

33. A method of providing ventilation gas, the method comprising:

providing a nasal interface system comprising;

a ventilator;

a gas delivery circuit;

at least one jet nozzle at a distal end of the gas delivery circuit;

at least one outer tube proximate to the distal end of the gas delivery circuit for receiving ventilation gas from the at least one jet nozzle, and wherein the at least one outer tube curves laterally away from a midline of a nose;

at least one sensor;

measuring spontaneous respiration with the at least one sensor; and

activating the ventilator to supply ventilation gas in synchrony with phases of breathing through the gas delivery circuit and to the at least one jet nozzle such that the ventilation gas entrains ambient air,

wherein the ventilation gas entrains ambient air.

34. The method of claim 33, wherein the ventilation gas and entrained ambient air elevates lung pressure, elevates lung volume, decreases work of breathing or increases airway pressure.

35. The method of claim 33, wherein ventilation gas is directed toward an inner wall of the at least one outer tube.

36. The method of claim 33, wherein the at least one nozzle is within the at least one outer tube.

37. The method of claim 33, wherein the at least one nozzle is flush with the at least one outer tube.

38. The method of claim 37, wherein the at least one nozzle is outside the at least one outer tube.

39. The method of claim 33, wherein the nasal interface system comprises a portable gas supply, and wherein the ventilator is portable.

40. The method of claim 33, wherein the supply of ventilation gas is adjusted to meet the needs of a patient based on information from the at least one sensor.

41. The method of claim 33, further comprising detecting speaking, and wherein the supply of ventilation gas is adjusted based on whether or not a patient is speaking.

42. The method of claim 33, further comprising detecting apnea or hypopnea, and wherein the supply of ventilation gas is adjusted based on apnea or hypopnea.