Anhydrous Antiperspirant Compositions with Improved Active Substance Release

• US 20100260698A1
• Filed: 06/25/2010
• Published: 10/14/2010
• Est. Priority Date: 12/28/2007
• Status: Abandoned Application

• Current Assignee: Henkel AG & Co KGaA
• Original Assignee: Henkel AG & Co KGaA
• Inventors: Banowski, Bernhard, Galante, Cheryl, Buse, Nadine
• Application Number:
  US12/823,484
• Publication Number:
  US 20100260698A1
• Time in Patent Office: Days
• US Class Current: 424/65
• CPC Class Codes: A61K 2800/31 Anhydrous
• CPC Class Codes: A61K 8/046 Aerosols; Foams
• CPC Class Codes: A61K 8/26 Aluminium; Compounds thereof
• CPC Class Codes: A61K 8/31 Hydrocarbons
• CPC Class Codes: A61K 8/37 Esters of carboxylic acids
• CPC Class Codes: A61K 8/585 Organosilicon compounds
• CPC Class Codes: A61K 8/891 saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
• CPC Class Codes: A61K 8/893 modified by an alkoxy or aryloxy group, e.g. behenoxy dimethicone or stearoxy dimethicone
• CPC Class Codes: A61K 8/894 modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
• CPC Class Codes: A61Q 15/00 Anti-perspirants or body deodorants deodorisation of air A61L9/00

Abstract

Antiperspirant compositions for personal body care, ready-made as a stick, soft solid, cream, gel, suspension, solution or impregnated on a substrate, containing at least one antiperspirant active substance, at least one oil, liquid under normal conditions, as a carrier, 0-3 wt. % by weight of free water, based on weight of the composition, and at least one organosiloxane oxyalkylene copolymer.

Claims

1. Antiperspirant composition for personal body care, ready-made as a non-aerosol, a stick, a soft solid, a cream, a gel, a suspension, a solution or impregnated on a substrate, comprising:

a) at least one antiperspirant active substance,

b) at least one oil, liquid under normal conditions, as a carrier,

c) 0-3 wt. % by weight of free water, based on total weight of the composition, and

d) at least one organosiloxane-oxyalkylene copolymer.

2. Composition according to claim 1, wherein the at least one organosiloxane-oxyalkylene copolymer is chosen from compounds of general structural formulae (I), (II), (III), (IV) and (V)

3. Composition according to claim 1, wherein the at least one organosiloxane-oxyalkylene copolymer is chosen from linear polysiloxane-polyoxyalkylene block copolymers.

4. Composition according to claim 1, wherein the at least one organosiloxane-oxyalkylene copolymer has an HLB value of from 8 to 20.

5. Composition according to claim 2, wherein the at least one organosiloxane-oxyalkylene copolymer is at least compounds according to general structural formula (II).

6. Composition according to claim 1, wherein the organosiloxane-oxyalkylene copolymer is an organosiloxane-oxyalkylene copolymer having an average number of silicon atoms per molecule of 15 or less.

7. Composition according to claim 2, wherein at least one organosiloxane-oxyalkylene copolymer is at least one organosiloxane-oxyalkylene copolymer of general structural formula (II) comprising an HLB value of 8-20, wherein

R¹=methyl,

R²═

—

(CH₂)₃—

O—

(C₂H₄O—

)₂₂ (C₃H₆O—

)₂₄CH₃

n=10-500, and

p=10-50.

8. Composition according to claim 2, wherein at least one organosiloxane-oxyalkylene copolymer is at least one organosiloxane-oxyalkylene copolymer of general structural formula (II) comprising an HLB value of 8-20, wherein

R¹=methyl group,

R²═

—

C_cH_2c—

O—

(C₂H₄O—

)_aR⁵,

with

a=5-20,

b=0,

c=3, and

R⁵=a hydrogen atom or a methyl group,

n=0, and

p=1.

9. Composition according to claim 2, wherein at least one organosiloxane-oxyalkylene copolymer is at least one organosiloxane-oxyalkylene copolymer of general structural formula (II) comprising an HLB value of 8-20, wherein

R¹=tert.-butyl group,

R²═

—

C_cH_2c—

O—

(C₂H₄O—

)_aR⁵,

with

a=5-20,

b=0,

c=3, and

R⁵=a hydrogen atom or a methyl group,

n=0, and

p=1.

10. Composition according to claim 2, wherein at least one organosiloxane-oxyalkylene copolymer is at least one organosiloxane-oxyalkylene copolymer of general structural formula (II) comprising an HLB value of 8-20, wherein

R¹=isopropyl group,

R²═

—

C_cH_2c—

O—

(C₂H₄O—

)_aR⁵,

with

a=5-20,

c=3, and

R⁵=a hydrogen atom or a methyl group,

n=0, and

p=1.

11. Composition according to claim 2, wherein at least one organosiloxane-oxyalkylene copolymer is at least one organosiloxane-oxyalkylene copolymer of general structural formula (II) comprising an HLB value of 8-20, wherein

R¹=methyl,

R²═

—

CH₂—

CH(CH₃)—

CH₂—

O—

(C₂H₄O—

)_aR⁵, with

a=5-20,

c=3, and

R⁵=a hydrogen atom or a methyl group,

n=0, and

p=1.

12. Composition according to claim 1, wherein the at least one organosiloxane-oxyalkylene copolymer is at least a linear polysiloxane-polyoxyethylene-polyoxypropylene block copolymer having 1NCI designation PEG/PPG-22/24 dimethicone.

13. Composition according to claim 1, wherein the at least one organosiloxane-oxyalkylene copolymer has a water solubility of at least 5 g per 100 g of aqueous solution.

14. Composition according to claim 1 further comprising at least one lipophilic thickener.

15. Composition according to claim 1, wherein the at least one oil carrier which is liquid under normal conditions is chosen from volatile cyclic or linear silicone oils, non-volatile higher molecular linear dimethylpolysiloxanes, esters of linear or branched, saturated or unsaturated fatty alcohols with 2-30 carbon atoms, linear or branched, saturated or unsaturated, optionally hydroxylated, fatty acids with 2-30 carbon atoms, benzoic acid esters of linear or branched C_8-22 alkanols, C₈-C₂₂ fatty alcohol esters of monohydric or polyhydric C₂-C₇ hydroxycarboxylic acids, addition products of ethylene oxide and/or propylene oxide on monohydric or polyhydric C_3-20 alkanols, liquid paraffin oils, isoparaffin oils, in particular isodecane, isoundecane, isododecane, isotridecane, isotetradecane, isopentadecane, isohexadecane and isoeicosane, synthetic hydrocarbons, such as polyisobutene or polydecenes, and alicyclic hydrocarbons, branched saturated or unsaturated fatty alcohols with 6-30 carbon atoms, mixtures of Guerbet alcohols and Guerbet alcohol esters, symmetrical, unsymmetrical or cyclic esters of carbonic acid with fatty alcohols, triglycerides of linear or branched, saturated or unsaturated, optionally hydroxylated C_8-30 fatty acids, dicarboxylic acid esters of linear or branched C₆-C₁₀ alkanols, di-n-alkylethers having 12 to 36C atoms, as well as mixtures thereof.

16. Composition according to claim 1, wherein the at least one oil carrier which is liquid under normal conditions is at least isoparaffin oil.

17. Composition according to claim 1, wherein the at least one oil carrier which is liquid under normal conditions is at least a mixture of volatile silicone oil chosen from cyclomethicone and linear polydimethylsiloxanes with 2-10 siloxane units and at least one isoparaffin oil.

18. Composition according to claim 1, wherein the at least one oil carrier which is liquid under normal conditions is at least a mixture of volatile silicone oil and at least one non-silicone oil chosen from branched, saturated or unsaturated fatty alcohols with 6-30 carbon atoms, triglycerides of linear or branched, saturated or unsaturated, optionally hydroxylated, C_8-30 fatty acids, dicarboxylic acid esters of linear or branched C₂-C₁₀ alkanols, esters of branched, saturated or unsaturated fatty alcohols with 2-30 carbon atoms with linear or branched, saturated or unsaturated fatty acids with 2-30 carbon atoms, optionally hydroxylated, addition products of 1 to 5 propylene oxide units on monohydric or polyhydric C_8-22 alkanols, addition products of at least 6 ethylene oxide and/or propylene oxide units on monohydric or polyhydric C_3-22 alkanols, C₈-C₂₂ fatty alcohol esters of monohydric or polyhydric C₂-C₇ hydroxycarboxylic acids, symmetrical, unsymmetrical or cyclic esters of carbonic acid with fatty alcohols, and esters of dimers of unsaturated C₁₂-C₂₂ fatty acids with monohydric linear, branched or cyclic C₂-C₁₈ alkanols or with polyhydric linear or branched C₂-C₆ alkanols.

19. Non-therapeutic cosmetic method for reducing and/or regulating formation of sweat and/or of body odor comprising:

applying an effective amount of a composition according to claim 1 onto skin.