Compositions and Methods for Improving or Preserving Brain Function
First Claim
1. A composition comprising medium chain triglycerides (MCT), in an amount effective for improving performance in, or reversing, preventing, reducing, or delaying decline in one or more of cognitive function, memory, motor performance, cerebrovascular function, or behavior in an aging mammal, wherein said composition increases a circulating concentration of at least one type of ketone body in the mammal;
- and wherein the MCT are of the formula;
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention is related to mammalian nutrition and effects thereof in individuals with age associated cognitive decline such as Age Associated Memory Impairment (AAMI) or a dementing illness such as Alzheimer'"'"'s disease or related dementia, or Mild Cognitive Impairment, such as improving performance in, or reversal, prevention, reducing and delaying decline in, one or more of cognitive function, memory, behavior, cerebrovascular function, motor function, and/or brain physiology are seen. In particular, the present invention utilizes medium chain triglycerides, in one embodiment, administered as part of a long-term treatment regimen, to preserve or improve learning, attention, motor performance, cerebrovascular function, social behavior, and to increase activity levels, particularly in aging mammals.
2 Citations
64 Claims
-
1. A composition comprising medium chain triglycerides (MCT), in an amount effective for improving performance in, or reversing, preventing, reducing, or delaying decline in one or more of cognitive function, memory, motor performance, cerebrovascular function, or behavior in an aging mammal, wherein said composition increases a circulating concentration of at least one type of ketone body in the mammal;
- and wherein the MCT are of the formula;
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
- and wherein the MCT are of the formula;
-
9. A method for improving performance in, or reversing, preventing, reducing, or delaying decline in at least one of cognitive function memory, motor function, cerebrovascular function, or behavior in an aging mammal comprising the steps of:
-
identifying an aging mammal having, or at risk of, decline in at least one of cognitive function memory, motor function, cerebrovascular function, or behavior; and administering to the mammal on an extended regular basis a composition comprising medium chain triglycerides (MCT) in an amount effective to improve performance in, or to reverse, prevent, reduce, or delay decline in at least one of cognitive function memory, motor function, cerebrovascular function, or behavior in the mammal wherein said composition increases the circulating concentration of at least one type of ketone body in the mammal; and
wherein the MCT are of the formula; - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
-
-
30. A method for improving performance in, or reversing, preventing, reducing, or delaying decline in at least one of cognitive function, memory, motor function, cerebrovascular function, or behavior in an aging mammal comprising the steps of:
-
(a) identifying an aging mammal not having an age-related cognitive impairment disease; and (b) administering to the mammal, on an extended regular basis, a composition comprising medium chain triglycerides (MCT) in an amount effective to improve performance in, or reverse, prevent, reduce, or delay decline in at least one of cognitive function, memory, motor function, cerebrovascular function, or behavior in the mammal; wherein said composition increases the circulating concentration of at least one type of ketone body in the mammal; and
wherein the MCT are of the formula; - View Dependent Claims (31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48)
-
-
49. A method for improving performance in, or reversing, preventing, reducing, or delaying decline in at least one of cognitive function, memory, motor function, cerebrovascular function, or behavior in a population of healthy aging mammals comprising the steps of:
-
(a) identifying a population of healthy aging mammals not having age-related cognitive impairment; (b) dividing the population into at least a control group and one or more test groups; (c) formulating at least one delivery system for delivering a composition comprising medium chain triglycerides (MCT) in an amount effective for elevating and maintaining an elevated level of at least one type of ketone body in the blood of an individual mammal;
wherein the MCT are of the formula; - View Dependent Claims (50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64)
-
Specification