AUTOINJECTOR

• US 20100268170A1
• Filed: 09/25/2008
• Published: 10/21/2010
• Est. Priority Date: 09/25/2007
• Status: Active Grant

• Current Assignee: Becton Dickinson France (Becton Dickinson & Co)
• Original Assignee: Becton Dickinson France (Becton Dickinson & Co)
• Inventors: Perot, Frederic, Carrel, Franck
• Granted Patent: US 8,568,359 B2
• Time in Patent Office: Days
• US Class Current: 604/198
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/208 Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
• CPC Class Codes: A61M 5/3272 having projections following labyrinth paths

Abstract

The invention relates to an autoinjector (1) comprising:

• • a housing (30, 30a, 30b), a container movable within said housing between an initial position and an insertion position, said movement being prevented when the container is in its passive state, and permitted when the container is in its active state, and
  • a safety shield (40) movable with respect to said housing between a first position and a second position, said movement placing the container in its active state,
  • first retaining means (61, 52) for maintaining said container in its passive state,
  • characterized in that it comprises
  • first deactivating means (50, 51), capable of rotating with respect to said first retaining means from a first position, in which said first retaining means maintain said container in its passive state, to a second position, in which said first retaining means allow the passage of said container in its active state, said rotation being caused by movement of said safety shield from its first position to its second position under distal pressure exerted on said housing.

Claims

1. A device (1) for automatic injection of a product (2) into an injection site, said device having a longitudinal axis A and comprising:

a housing (30, 30a, 30b) capable of receiving a container, said container being provided at one distal end with a needle (3) and being movable relative to said housing between an initial position in which a distal end of said needle does not extend beyond a distal end of said housing and in which the container is in one of a passive state and an active state, to an insertion position, distally spaced relative to said initial position, in which said distal end of said needle extends beyond said distal end of said housing, movement of the container out of its initial position being prevented when the container is in its passive state, and being permitted when the container is in its active state, and

a safety shield (40) coupled to and movable with respect to said housing between a first position and a second position, proximally spaced with respect to said first position, said safety shield (40) having a free end that is distally spaced beyond a distal end of the needle when said safety shield (40) is on said second position, movement of said safety shield from its first position to its second position placing the container in its active state,

first retaining means (61, 52) for maintaining the container in its passive state,

said device being characterized in that it comprises

first deactivating means (50, 51), capable of rotating with respect to said first retaining means around said longitudinal axis A from a first position, in which said first retaining means maintain the container in its passive state, to a second position, in which said first retaining means are deactivated and allow the passage of the container in its active state, rotation around said longitudinal axis A of said first deactivating means from its first position to its second position being caused by movement of said safety shield from its first position to its second position under distal pressure exerted on said housing.

2. Device (1) according to claim 1, wherein it further comprises:

first biasing means (100) coupled to said housing for biasing the container toward said insertion position, said first biasing means being in one of a compressed condition, in which the container is in its initial position, and an extended condition, in which the container is in its insertion position, and

second retaining means (31, 71) for maintaining said first biasing means in its compressed condition,

triggering means (80) being activatable by application of a force on said triggering means to release said second retaining means, said triggering means being in one of a passive state, in which application of said force on said triggering means cannot cause the release of said second retaining means, and an active state in which application of said force on said triggering means causes the release of said second retaining means, wherein movement of said safety shield from its first position to its second position causes passage of said triggering means from its passive state to its active state.

3. Device (1) according to claim 2, wherein it further comprises:

third retaining means (58, 81) for maintaining said triggering means in its passive state,

second deactivating means (50, 57), capable of rotating with respect to said third retaining means around said longitudinal axis A from a blocked position, in which said third retaining means maintain said triggering means in its passive state, to a free position, in which said third retaining means allow the passage of said triggering means in its active state, rotation around said longitudinal axis A of said second deactivating means from its blocked position to its free position being caused by movement of said safety shield from its first position to its second position.

4. Device (1) according to claim 3, wherein part of said first and second deactivating means are formed on at least one intermediate sleeve (50) received within said housing, said intermediate sleeve (50) being movable in rotation around said longitudinal axis A from a first position to a second position in response to movement of said safety shield at least out of its first position.

5. Device (1) according to claim 4, wherein

said first retaining means comprising at least a ring (60) received within said safety shield and coupled to said container, said ring comprising at least an outer radial stop (61),

said first deactivating means comprises a window (51) arranged in said intermediate sleeve (50), said window comprising an abutment surface (52),

said radial stop being engaged on said abutment surface in the first position of said intermediate sleeve, and being disengaged from said abutment surface after rotation of said intermediate sleeve around said longitudinal axis A.

6. Device (1) according to claim 4, wherein:

said third retaining means comprising at least a distal leg (81) located on said triggering means (80) in regard of the proximal end (58) of said intermediate sleeve (50),

said second deactivating means comprise a proximal recess (57) arranged at the proximal end of said intermediate sleeve (50),

said distal leg being in spaced relation to the proximal end (58) of said intermediate sleeve in the first position of said intermediate sleeve, and being in regard with said recess (57) after rotation around said longitudinal axis A of the intermediate sleeve, thereby allowing distal movement of said triggering means by application of a force exerted on said triggering means.

7. Device (1) according to claim 6, wherein it further comprises guiding means (41, 56, 56a;

141, 151) designed for causing the rotation around said longitudinal axis A of said intermediate sleeve with respect to said safety shield when distal pressure is exerted on said housing.

8. Device (1) according to claim 7, wherein said guiding means include at least a peg (41;

151) located on said intermediate sleeve or on said safety shield and a first cam (56a;

141) located respectively on said safety shield or on said intermediate sleeve and in which said peg is engaged so as to be able to move slidingly and reversibly within said first cam, said first cam being inclined with respect to the longitudinal axis A of said device, the movement of said peg within said first cam when distal pressure is applied on said housing causing rotation of said intermediate sleeve around said longitudinal axis A.

9. Device (1) according to claim 6, wherein it comprises first return means (110;

152) designed for biasing said safety shield from its second position to its first position when distal pressure exerted on said housing is released before activation of said triggering means, said guiding means causing the intermediate sleeve to rotate back in its first position around said longitudinal axis A.

10. Device (1) according to claim 9, wherein said first return means comprise at least a spring (110), said spring being in a compressed condition when said safety shield is in its second position.

11. Device (1) according to claim 9, wherein said first return means further comprise a flexible tab (152) located on said intermediate sleeve, said flexible tab being in a rest position when said intermediate sleeve is in its first position and being in a tangentially deflected position when said intermediate sleeve is in its second position, said intermediate sleeve being movable in rotation around said longitudinal axis A with respect to said housing, said flexible tab having a radial protrusion (154) engaged in a window (130) located on said housing, said flexible tab aiming at coming back to its rest position when distal pressure exerted on said housing is released, thereby causing said intermediate sleeve to rotate back to its first position around said longitudinal axis A.

12. Device (1) according to claim 6, wherein it further comprises locking means designed for preventing the intermediate sleeve to rotate back around said longitudinal axis A to its first position when distal pressure exerted on said housing is released after activation of said triggering means but before the container reaches its insertion position, said locking means comprising a lateral wall (58a) of said recess, said distal leg being at least in abutment on said lateral wall after activation of said triggering means, thereby preventing the rotation around said longitudinal axis A of said intermediate sleeve with respect to said triggering means.

13. Device (1) according to claim 12, wherein said distal leg comprises at least one tooth (181) and said lateral wall comprises at least one groove (158), said at least one tooth being caused to engage said at least one groove if distal pressure exerted on said housing is released after activation of said triggering means and before the container reaches its insertion position, so that further activation of said triggering means is prevented.

14. Device (1) according to claim 12, wherein:

said safety shield being movable with respect to the container to a third position, in which the tip of the needle extends beyond a distal end of said safety shield, and to a fourth position, in which the tip of the needle does not extend beyond a distal end of said safety shield,

said device further comprises

second biasing means (110) coupled to said safety shield for biasing said safety shield from its third position to its fourth position when distal pressure exerted on said housing is released,

first arresting means (56d) designed for maintaining said safety shield substantially in its third position, if distal pressure exerted on said housing is released after activation of said triggering means and before the container reaches its insertion position,

third deactivating means (54, 60) designed for deactivating said first arresting means when the container is in its insertion position.

15. Device (1) according to claim 14, wherein said first arresting means comprise an abutment surface (56d) formed in said first cam (56a), said peg (41) coming in abutment on said abutment surface and thereby preventing further movement of said safety shield with respect to said intermediate sleeve when distal pressure exerted on said housing is released after activation of said triggering means and before the container reaches its insertion position.

16. Device (1) according to claim 15, wherein

said first retaining means comprising at least a ring (60) received within said safety shield and coupled to said container, said ring comprising at least an outer radial stop (61), said ring being coupled to the container,

said first deactivating means comprises a window (51) arranged in said intermediate sleeve (50), said window comprising an abutment surface (52),

said radial stop being engaged on said abutment surface in the first position of said intermediate sleeve, and being disengaged from said abutment surface after rotation of said intermediate sleeve around said longitudinal axis A, and

wherein said third deactivating means comprise an inclined slope (54) located in said window (51), said radial stop (61) of said ring cooperating with said slope so as to cause a further rotation around said longitudinal axis A of said intermediate sleeve with respect to said safety shield, when the container moves from its initial position to its insertion position, thereby causing said peg to disengage from said abutment surface and to engage the proximal end of a second cam (56c) formed on said intermediate sleeve or on said safety shield, said second cam extending longitudinally in the distal direction.

17. Device (1) according to claim 16, wherein it further comprises second arresting means (59) for preventing the movement of said safety shield from its fourth position to its third position.

18. Device (1) according to claim 17, wherein said second arresting means comprise a flexible tab (59) located in the distal region of said second cam (56c), said flexible tab being able to be overcome by said peg during the movement of said safety shield from its third position to its fourth position, said flexible tab forming a stop with respect to the proximal movement of said peg when said safety shield is in its fourth position.

19. Device (1) according to claim 2, wherein said first deactivating means (50) is capable of rotating around said longitudinal axis A from its second position to its first position, said rotation being caused by movement of said safety shield (40) from its second position to its first position prior to activation of the triggering means (80).