DEVICE AND METHOD FOR MODULATING RENAL FUNCTION
First Claim
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1. A device, comprising:
- a controller contained within an implantable housing;
a physiological sensor interfaced to the controller for measuring a physiological variable; and
,an occluding structure adapted for implantation around a renal lymphatic vessel and operable by the controller to pinch the renal lymphatic vessel and thereby restrict flow therethrough;
wherein the controller is programmed to operate the occluding structure in response to the measured physiological variable.
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Abstract
Renal function may be modulated by an implantable device having one or more leads or catheters disposed near the kidney via the lymphatic system. In one embodiment, lymphatic drainage from the kidney is modulated to increase or decrease tubular reabsorption of salt and water. The renal function modulation therapy may be delivered in an open-loop or closed-loop fashion, with the latter dependent upon a physiological variable such as blood pressure or cardiac output.
15 Citations
20 Claims
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1. A device, comprising:
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a controller contained within an implantable housing; a physiological sensor interfaced to the controller for measuring a physiological variable; and
,an occluding structure adapted for implantation around a renal lymphatic vessel and operable by the controller to pinch the renal lymphatic vessel and thereby restrict flow therethrough; wherein the controller is programmed to operate the occluding structure in response to the measured physiological variable. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification