ENVIRONMENT TEMPERATURE MEASURING METHOD, LIQUID SAMPLE MEASURING METHOD, AND MEASURING DEVICE

• US 20100268475A1
• Filed: 03/27/2009
• Published: 10/21/2010
• Est. Priority Date: 03/27/2008
• Status: Abandoned Application

• Current Assignee: Panasonic Healthcare Holdings Co., Ltd.
• Original Assignee: Panasonic Healthcare Holdings Co., Ltd.
• Inventors: Kusumoto, Kunimasa
• Application Number:
  US12/747,711
• Publication Number:
  US 20100268475A1
• Time in Patent Office: Days
• US Class Current: 702/19
• CPC Class Codes: G01K 7/42 Circuits effecting compensation of thermal inertia; Circuits for predicting the stationary value of a temperature
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G01N 27/3273 Devices therefor, e.g. test element readers, circuitry details not specific to biochemical electrodes G01N33/4875
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771

Abstract

A cavity (17) in which an analysis sample is held and measurement is performed, and an electrode system (14) for measuring the concentration of the sample in the cavity (17) are provided on a biosensor (1). A secondary cell (21) and an environment temperature sensor (9) are provided inside the measuring device (2). The environment temperature during charging is measured in real time by specifying the environment temperature during charging from the time required to charge the secondary cell (21) and the environment temperature during charging. The measured analysis sample concentration is corrected for temperature with high accuracy from the environment temperature information obtained during charging, in a temperature correction step 09, and thus an analysis result with extremely high accuracy is obtained.

Claims

1. An environment temperature measuring method for measuring the temperature with a measuring device provided with a heat generating material and an environment temperature sensor inside a housing, on the basis of electrical information measured by the environment temperature sensor, said method comprising:

a heat generation operating time measuring step of measuring the operating time during heat generation by a heat generating material provided inside the housing; and

an external environment temperature calculation step of calculating the external environment temperature outside the housing on the basis of the operating time of the heat generating material and an internal environment temperature obtained at the environment temperature sensor.

2. The environment temperature measuring method according to claim 1,

wherein, in the external environment temperature calculation step, the external environment temperature outside the housing is calculated on the basis of an environment temperature calculation table stored in a memory device provided inside the housing.

3. The environment temperature measuring method according to claim 1,

wherein, in the external environment temperature calculation step, the external environment temperature outside the housing is calculated on the basis of the operating time of the heat generating material and the difference between a plurality of detection results for internal environment temperature information at a plurality of environment temperature sensors provided inside the housing.

4. The environment temperature measuring method according to claim 1,

further comprising a correction step of performing temperature correction for various correction categories by using the external environment temperature calculated in the external environment temperature calculation step.

5. The environment temperature measuring method according to claim 1,

wherein the heat generating material is one or more of a secondary cell, a battery, a charger, a charging IC, a coil (inductor), and a resistor.

6. The environment temperature measuring method according to claim 5,

wherein the external environment temperature calculation step involves calculating the external environment temperature on the basis of the internal environment temperature information and the operating time of the secondary cell measured in the heat generation operating time measurement step, regardless of whether or not charging is in progress.

7. The environment temperature measuring method according to claim 6,

wherein, in the external environment temperature calculation step, an appropriate selection is made from a plurality of the specific environment temperature calculation tables and the external environment temperature is calculated, either during or after charging.

8. The environment temperature measuring method according to claim 5, further comprising:

a determination step of determining whether or not the difference between the internal environment temperature measurement information measured by the environment temperature sensor and the temperature data included in the environment temperature calculation table exceeds a specific range; and

an error notification step of judging an error to have occurred and notifying to that effect when it is determined in the determination step that the specific range has been exceeded.

9. The environment temperature measuring method according to claim 5,

wherein, in the external environment temperature calculation step, after the completion of charging, shared information from the environment temperature calculation table is used.

10. The environment temperature measuring method according to claim 5,

wherein, in the external environment temperature calculation step, during a time period from right after the start of charging until a specific length of time has elapsed, shared information from the environment temperature calculation table is used.

11. The environment temperature measuring method according to claim 3,

wherein the heat generating material is one or more of a secondary cell, a battery, a charger, a charging IC, a coil (inductor), and a resistor.

12. The environment temperature measuring method according to claim 11,

wherein the external environment temperature calculation step involves calculating the external environment temperature on the basis of the operating time of the secondary cell measured in the heat generation operating time measurement step and the measurement results of a plurality of the environment temperature sensors installed in the measuring device, regardless of whether or not charging is in progress.

13. The environment temperature measuring method according to claim 12,

wherein, in the external environment temperature calculation step, an appropriate selection is made from a plurality of environment temperature calculation tables and the external environment temperature is calculated, either during or after charging.

14. The environment temperature measuring method according to claim 12, further comprising:

a determination step of determining whether or not the difference between the measurement results of the plurality of environment temperature sensors exceeds a specific range; and

an error notification step of judging an error to have occurred and notifying to that effect when it is determined in the determination step that the specific range has been exceeded.

15. A liquid sample measuring method, in which the concentration of a specific component in a liquid sample deposited on a biosensor mounted in a measuring device provided with a heat generating material and an environment temperature sensor inside a housing is measured, said method comprising:

a specimen concentration measurement step of measuring the concentration of the specific component in the liquid sample deposited on the biosensor; and

an external environment temperature correction step of correcting the concentration of the specific component on the basis of the external environment temperature outside the housing as found by the environment temperature measuring method according to claim 1.

16. The liquid sample measuring method according to claim 15,

wherein the external environment temperature calculation step includes an internal environment temperature measurement step of measuring the internal environment temperature inside the housing with an environment temperature sensor that is provided near a biosensor holding section provided in the housing and to which the biosensor can be removably attached, or near an opening in the measuring device.

17. The liquid sample measuring method according to claim 15,

wherein the external environment temperature calculation step includes an internal environment temperature measurement step of measuring the internal environment temperature inside the housing with an environment temperature sensor that is mounted in a biosensor holding section provided in the housing and to which the biosensor can be removably attached, and that is provided near an electrode terminal on the biosensor.

18. The liquid sample measuring method according to claim 15,

wherein, if the specimen concentration measurement step is started during the heat generation operating time measurement step, then the heat generation operating time measurement step is carried out in parallel with the specimen concentration measurement step.

19. The liquid sample measuring method according to claim 15,

wherein, if the specimen concentration measurement step is started during the heat generation operating time measurement step, then the heat generation operating time measurement step is carried out in parallel with the specimen concentration measurement step only for a predetermined length of time from the start of measurement of the heat generation operating time.

20. The liquid sample measuring method according to claim 15,

wherein the external environment temperature correction step includes an internal environment temperature correction step of correcting the concentration of a specific component in the liquid sample deposited on the biosensor, on the basis of the internal environment temperature inside the housing as measured in the internal environment temperature measurement step.

21. The liquid sample measuring method according to claim 15,

wherein the external environment temperature correction step includes a correction category temperature correction step of correcting various correction categories other than the temperature at which the concentration of a specific component in the liquid sample is corrected as obtained in the specimen concentration measurement step, on the basis of information about the internal environment temperature inside the housing measured by the environment temperature sensor, or information about the environment temperature outside the housing as calculated in the external environment temperature calculation step.

22. The liquid sample measuring method according to claim 15,

wherein, in the external environment temperature calculation step, a correction is performed when the difference between the values of the internal environment temperature information and the external environment temperature information exceeds a specific threshold.

23. The liquid sample measuring method according to claim 15,

wherein, in the external environment temperature calculation step, the internal environment temperature inside the housing is corrected after detecting that the liquid sample has been deposited on the biosensor, on the basis of the charging operating time information calculated in the heat generation operating time measurement step.

24. The liquid sample measuring method according to claim 15,

wherein, in the external environment temperature correction step, the optimal environment temperature calculation table, according to the operating time during heat generation of the heat generating material, is selected from among the plurality of environment temperature calculation tables stored in the memory device provided to the measuring device, and the concentration of a specific component in the liquid sample is corrected.

25. The liquid sample measuring method according to claim 21,

wherein, in the correction category temperature correction step, a plurality of the environment temperature calculation tables stored in the memory device provided to the measuring device are selected according to the charging operating time information during heat generation of the heat generating material, and temperature correction is also performed for various correction categories other than temperature that are performed before and after the temperature correction of the specific component concentration.

26. A measuring device, comprising:

a housing;

a heat generating material provided inside the housing;

an environment temperature sensor provided inside the housing, configured to measure the internal environment temperature inside the housing;

an operating time measurement component configured to measure the operating time of the heat generating material; and

a computer configured to compute external environment temperature information for the outside of the housing, on the basis of the internal environment temperature and the operating time during heat generation of the heat generating material.

28. The measuring device according to claim 26,

wherein a plurality of the environment temperature sensors are provided inside the housing, and

the computer calculates the external environment temperature on the basis of the operating time during heat generation of the heat generating material, and a plurality of internal environment temperatures measured at the plurality of environment temperature sensors.

29. The measuring device according to claim 26,

wherein the environment temperature sensor is disposed inside the biosensor holding section.

30. The measuring device according to claim 26,

wherein the environment temperature sensor is at least provided near the opening of the biosensor holding section.

31. The measuring device according to claim 26,

wherein at least one of the plurality of environment temperature sensors is provided near the heat generating material.

32. The measuring device according to claim 26,

wherein the computer further performs correction for various correction categories other than the temperature at which the concentration of a specific component in the liquid sample deposited on the biosensor is corrected, on the basis of the external environment temperature outside the measuring device.

33. The measuring device according to claim 26,

further comprising a memory device configured to store a plurality of environment temperature calculation tables for computing the external environment temperature outside the housing, on the basis of the operating time and the internal environment temperature.

34. The measuring device according to claim 26,

wherein the heat generating material is one or more of a secondary cell, a battery, a charger, a charging IC, a coil (inductor), and a resistor.

35. The measuring device according to claim 34,

wherein the computer calculates the external environment temperature on the basis of the internal environment temperature and the operating time of the secondary cell measured by the operating time measurement component, regardless of whether or not charging is in progress.

36. The measuring device according to claim 34,

wherein the computer makes an appropriate selection from a plurality of the specific environment temperature calculation tables and calculates the external environment temperature, either during or after charging.

37. The measuring device according to claim 34, further comprising:

a determination component configured to determine whether or not the difference between the internal environment temperature measurement measured by the environment temperature sensor and the temperature data included in the environment temperature calculation table exceeds a specific range; and

an error notification component configured to judge an error to have occurred and notifying to that effect when it is determined by the determination component that the specific range has been exceeded.

38. The measuring device according to claim 34,

wherein the computer uses shared information from the environment temperature calculation table after the completion of charging.

39. The measuring device according to claim 34,

wherein the computer uses shared information from the environment temperature calculation table during a time period from right after the start of charging until a specific length of time has elapsed.

40. The measuring device according to claim 28,

wherein the heat generating material is one or more of a secondary cell, a battery, a charger, a charging IC, a coil (inductor), and a resistor.

41. The measuring device according to claim 40,

wherein the computer calculates the external environment temperature on the basis of the measurement result at the plurality of environment temperature sensors disposed inside the measuring device, regardless of whether or not charging is in progress.

42. The measuring device according to claim 40,

wherein the computer makes an appropriate selection from the information in the plurality of specific environment temperature calculation tables and performs correction, either during or after charging.

43. The measuring device according to claim 40, further comprising:

a determination component configured to determine whether or not the difference between the measurement results of the plurality of environment temperature sensors has exceeded a specific range; and

an error notification component configured to judge an error to have occurred and notifying to that effect when it is determined by the determination component that the specific range has been exceeded.

44. The measuring device according to claim 43, wherein there are:

a first region provided near the heat generating material inside the housing, and

a second region provided at a different position from that of the first region inside the housing,

a plurality of environment temperature sensor are provided in each of the first and second regions,

the determination component determines whether or not either the difference between the detection results for internal environment temperature information at a plurality of environment temperature sensors provided in the first region, or the difference between the detection results for internal environment temperature information at a plurality of environment temperature sensor provided in the second region, has exceeded a specific range, and

the error notification component judges an error to have occurred and notifies to that effect when it is determined by the determination component that the difference has exceeded the specific range.

45. The measuring device according to claim 34, comprising:

a remaining charge measurement component configured to measure the remaining charge of the secondary cell; and

a charging circuit configured to charge the secondary cell by supplying a specific current.

46. The measuring device according to claim 45,

wherein the computer estimates the charging completion time for the secondary cell on the basis of the charging current, the remaining charge, and the internal environment temperature and operating time during heat generation of the secondary cell.

47. The measuring device according to claim 45,

further having a display component configured to display various measurement information or status information,

wherein the charging completion time is displayed on the display component.

27. A measuring device equipped with a biosensor, configured to measure the concentration of a specific component deposited on the biosensor, said measuring device comprising:

a housing;

a heat generating material provided inside the housing;

an environment temperature sensor provided inside the housing, configured to measure the internal environment temperature inside the housing;

a measurement-use connection terminal configured to take off signals required for analysis from a measurement-use electrode on the biosensor side;

a biosensor holding section formed integrally with respect to the housing, configured to hold the biosensor in a removable state;

an operating time measurement component configured to measure the operating time of the heat generating material; and

a computer configured to compute external environment temperature for the outside of the housing, on the basis of the internal environment temperature measured at the environment temperature sensor and the operating time measured at the operating time measurement component.