ENZYMATIC REAGENT INK
First Claim
1. An enzymatic reagent ink for use in analytical test strips comprising:
- an amount of hydrophobic silica material;
an amount of surfactant; and
an amount of enzyme,wherein the amounts of the hydrophobic silica material and the surfactant in the enzymatic reagent ink is predetermined based on;
a first relationship between wetability of a representative hydrophobic silica material and at least a first calibration characteristic of an analytical test strip that includes an enzymatic reagent ink containing the representative hydrophobic silica material, the first relationship defining a minimum wetability that provides an acceptable first calibration characteristic; and
a second relationship defining wetability of a mixture of the hydrophobic silica material and the surfactant across a range of relative amounts of the hydrophobic silica material and the surfactant,such that the amounts of the hydrophobic silica material and the surfactant provide at least the minimum wetability defined by the first relationship during manufacturing of the enzymatic reagent ink.
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Accused Products
Abstract
An enzymatic reagent ink includes an amount of hydrophobic silica material (e.g., a fumed silica material), an amount of surfactant (such as a non-ionic surfactant); and an amount of enzyme (for example, glucose oxidase). The amounts of the hydrophobic silica material and the surfactant present in the enzymatic reagent ink is predetermined based on first and second relationships. The first relationship is a relationship between wetability of a representative hydrophobic silica material and a first calibration characteristic of an analytical test strip that includes an enzymatic reagent ink containing the representative hydrophobic silica material. In addition, such a first relationship defines a minimum wetability that provides an acceptable first calibration characteristic. The second relationship is a relationship defining wetability of a mixture of the hydrophobic silica material and a surfactant across a range of relative amounts of the hydrophobic silica material and the surfactant. The amounts of the hydrophobic silica material and the surfactant in the enzymatic reagent ink are predetermined to provide at least the minimum wetability defined by the first relationship during manufacturing of the enzymatic reagent ink, and therefore, an acceptable first calibration characteristic.
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Citations
12 Claims
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1. An enzymatic reagent ink for use in analytical test strips comprising:
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an amount of hydrophobic silica material; an amount of surfactant; and an amount of enzyme, wherein the amounts of the hydrophobic silica material and the surfactant in the enzymatic reagent ink is predetermined based on; a first relationship between wetability of a representative hydrophobic silica material and at least a first calibration characteristic of an analytical test strip that includes an enzymatic reagent ink containing the representative hydrophobic silica material, the first relationship defining a minimum wetability that provides an acceptable first calibration characteristic; and a second relationship defining wetability of a mixture of the hydrophobic silica material and the surfactant across a range of relative amounts of the hydrophobic silica material and the surfactant, such that the amounts of the hydrophobic silica material and the surfactant provide at least the minimum wetability defined by the first relationship during manufacturing of the enzymatic reagent ink. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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Specification