STENTS HAVING CONTROLLED ELUTION
First Claim
Patent Images
1. A device comprisinga. a stent;
- andb. a coating on the stent;
wherein the coating comprises at least one bioabsorbable polymer and at least one active agent;
wherein the active agent is present in crystalline form on at least one region of an outer surface of the coating opposite the stent and wherein 50% or less of the total amount of active agent in the coating is released after 24 hours in vitro elution.
6 Assignments
0 Petitions
Accused Products
Abstract
Provided herein is a device comprising: a. stent; b. a plurality of layers on said stent framework to form said device; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
-
Citations
54 Claims
-
1. A device comprising
a. a stent; - and
b. a coating on the stent;
wherein the coating comprises at least one bioabsorbable polymer and at least one active agent;
wherein the active agent is present in crystalline form on at least one region of an outer surface of the coating opposite the stent and wherein 50% or less of the total amount of active agent in the coating is released after 24 hours in vitro elution. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
- and
-
34. A device comprising
a. a stent; - and
b. a coating on the stent;
wherein the coating comprises at least one polymer and at least one active agent;
wherein the active agent is present in crystalline form on at least one region of an outer surface of the coating opposite the stent and wherein between 25% and 50% of the total amount of active agent in the coating is released after 24 hours in vitro elution. - View Dependent Claims (35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54)
- and
Specification