CONTAINER FOR TRANSDERMAL DELIVERY OF ACTIVE AGENT USING MICRONEEDLES

• US 20100274203A1
• Filed: 06/29/2010
• Published: 10/28/2010
• Est. Priority Date: 01/20/2009
• Status: Abandoned Application

• Current Assignee: Miti Systems, Inc.
• Original Assignee: Miti Systems, Inc.
• Inventors: Han, Man Hee, Sul, Boo Joon, Lee, Seung Seob
• Application Number:
  US12/826,009
• Publication Number:
  US 20100274203A1
• Time in Patent Office: Days
• US Class Current: 604/272
• CPC Class Codes: A61J 1/14 Details; Accessories therefor A61J7/00 takes precedence; openers B65D, B67B7/00
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 37/0015 by using microneedles

Abstract

A container for transdermal delivery of an active agent or agents using microneedles includes a reservoir adapted to receive a substance containing an active agent or agents; and a cover member adapted to cover an entrance of the reservoir, the cover member comprising one or more through-holes formed therein and one or more microneedles formed thereon. With the container, transdermal delivery can be made conveniently, easily, and effectively.

Claims

1. A container for transdermal delivery of an active agent or agents using microneedles, the container comprising:

a reservoir adapted to receive a substance containing an active agent or agents; and

a cover member adapted to cover an entrance of the reservoir, the cover member comprising one or more through-holes formed therein and one or more microneedles formed thereon.

2. The container according to claim 1, wherein the total area of the through-holes is less than 3 mm².

3. The container according to claim 1, wherein the cover member includes a guide groove formed on the top surface thereof so as to guide the flow of the substance containing the active agent or agents.

4. The container according to claim 1, wherein the cover member is detachably coupled to the top surface of the entrance of the reservoir.

5. The container according to claim 4, wherein the total area of the through-holes is less than 3 mm².

6. The container according to claim 4, wherein the cover member includes a guide groove formed on the top surface thereof so as to guide the flow of the substance containing the active agent or agents.

7. The container according to claim 1, wherein the cover member comprise:

a cap assembled and coupled to the entrance of the reservoir, the cap including an opening formed centrally therein; and

a microneedle substrate interposed between the cap and the top surface of the entrance of the reservoir, the microneedle substrate including one or more through-holes formed therein and one or more microneedles protrudingly formed thereon.

8. The container according to claim 7, wherein the total area of the through-holes is less than 3 mm².

9. The container according to claim 7, wherein the cover member comprises guide grooves formed on the top surface thereof so as to guide the flow of the substance containing the active agent or agents.

10. The container according to claim 7, further comprising an elastic layer interposed between the top surface of the entrance of the reservoir and the microneedle substrate, the elastic layer including an opening formed centrally therein to correspond to the entrance of the reservoir.

11. The container according to claim 10, wherein the total area of the through-holes is less than 3 mm².

12. The container according to claim 11, wherein the cover member comprises guide grooves formed on the top surface thereof so as to guide the flow of the substance containing the active agent or agents.

13. The container according to claim 1, further comprising at least one additional cap for covering the cover member.