LACRIMAL IMPLANT BODY INCLUDING COMFORTING AGENT
4 Assignments
0 Petitions
Accused Products
Abstract
Lacrimal implants for treating ocular diseases are disclosed. More particularly, lacrimal punctal plugs, methods of making such plugs, and methods of treating ocular diseases using such plugs are disclosed.
64 Citations
84 Claims
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1. (canceled)
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2. A punctum plug insertable into a lacrimal punctum for release of one or more comforting agents to an eye, the punctum plug comprising:
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a plug body having a proximal end portion adapted to be disposed near the punctal opening and a distal end portion adapted to be disposed within the punctal canal; wherein the punctum plug provides release of the one or more comforting agents to the eye. - View Dependent Claims (3, 5, 7, 9, 10, 11, 13, 14, 17)
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4. (canceled)
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6. (canceled)
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8. (canceled)
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12. (canceled)
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15-16. -16. (canceled)
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18-20. -20. (canceled)
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21. A punctum plug insertable into a lacrimal punctum for release of a therapeutic agent or agents, a comforting agent or agents, or both to an eye, the punctum plug comprising:
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a plug body having a proximal end portion adapted to be disposed near the punctal opening and a distal end portion adapted to be disposed within the punctal canal; an agent core at or near the proximal end portion; a retention structure at or near the distal end portion; and wherein the agent core or the plug body has at least one surface that provides release of the therapeutic agent or agents, the comforting agent or agents, or both, to the eye. - View Dependent Claims (22, 24, 25, 27, 28, 29, 30, 31, 33, 35, 36, 37, 43, 44, 45)
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23. (canceled)
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26. (canceled)
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32. (canceled)
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34. (canceled)
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38-42. -42. (canceled)
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46-53. -53. (canceled)
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54. A method of manufacturing a punctum plug insertable into a lacrimal punctum for release of one or more comforting agents to an eye, the method comprising:
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forming a plug body having a proximal end portion adapted to be disposed near the punctal opening and a distal end portion adapted to be disposed within the punctal canal; wherein the punctum plug provides release of the one or more comforting agents to the eye. - View Dependent Claims (55, 56)
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57. (canceled)
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58. A method to treat a subject having an eye disorder, comprising:
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inserting a punctum plug into at least one lacrimal punctum of the subject, the punctum plug comprising, a plug body having a proximal end portion adapted to be disposed near the punctal opening and a distal end portion adapted to be disposed within the punctal canal; wherein the plug body comprises an agent core at or near the proximal end portion and a retention structure at or near the distal end portion; wherein the agent core comprises a therapeutic agent or agents and has at least one surface providing release of the therapeutic agent or agents to the eye; and wherein the agent core, plug body or both provide release of a comforting agent or agents to the eye. - View Dependent Claims (59, 60, 61, 62, 63, 68, 72, 74, 78, 81, 82, 83)
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64-67. -67. (canceled)
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69-71. -71. (canceled)
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73. (canceled)
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75-77. -77. (canceled)
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79-80. -80. (canceled)
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84. (canceled)
Specification