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Topical Therapeutic Delivery System

  • US 20100278759A1
  • Filed: 02/08/2007
  • Published: 11/04/2010
  • Est. Priority Date: 02/08/2006
  • Status: Abandoned Application
First Claim
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1. An oil-in-water emulsion topical delivery system comprising (i) an oil phase;

  • (ii) an aqueous phase;

    (iii) phenoxyethanol at a concentration of from about 2.0% to about 2.7% based on the total weight of the composition;

    (iv) an effective exfoliating amount of a hydrophobic hydroxycarboxylic acid selected from the group consisting of orthohydroxybenzoic acid, hydroxycarboxylic acids containing a C12-C24 fatty acid esterified to the alpha carbon hydroxyl group, hydroxycarboxylic acids containing a C12-C24 fatty alcohol esterified to a carboxyl group;

    (v) a non-ionic emulsifier having an HLB of from about 7 to about 10; and

    (vi) at least one skin-supporting or dermatopharmaceutically active agent.

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