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Method and System for Multi-Component Heart and Aorta Modeling for Decision Support in Cardiac Disease

  • US 20100280352A1
  • Filed: 04/30/2010
  • Published: 11/04/2010
  • Est. Priority Date: 05/01/2009
  • Status: Active Grant
First Claim
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1. A method for multi-component heart modeling and cardiac disease decision support, comprising:

  • generating a multi-component patient specific 4D geometric model of the heart and aorta estimated from a sequence of volumetric cardiac imaging data of a patient generated using at least one medical imaging modality;

    generating a patient specific 4D computational model based on one or more of personalized geometry, material properties, fluid boundary conditions, and flow velocity measurements in the 4D geometric model;

    generating a patient specific biomechanical model based on Fluid Structure Interaction (FSI) simulations using the 4D computational model;

    extracting patient specific clinical parameters based on the 4D geometric model and the FSI simulations; and

    performing disease progression modeling and risk stratification based on the patient specific clinical parameters.

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