PERCUTANEOUS METHOD AND DEVICE TO TREAT DISSECTIONS

• US 20100280588A1
• Filed: 04/30/2010
• Published: 11/04/2010
• Est. Priority Date: 05/01/2009
• Status: Active Grant

• Current Assignee: Endologix
• Original Assignee: Endologix
• Inventors: Schreck, Stefan G.
• Granted Patent: US 9,579,103 B2
• Time in Patent Office: Days
• US Class Current: 623/1.11
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12099 characterised by the location of the occluder
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm

Abstract

Some embodiments of the present disclosure are directed to methods and systems for percutaneously treating dissections in a patient'"'"'s vasculature, such as, without limitation, the aorta. The method can include deploying a catheter containing a collapsed anchoring element, frame, and cover through a first vessel to an entry point of the dissection. In some embodiments, the anchoring element can be secured to the second branch vessel. The frame can be expanded in the first branch vessel. The cover can be unfolded over at least a portion of the entry point. The cover then reduces blood flow into the entry point.

Claims

1. A method for treating a vascular dissection, comprising:

advancing a catheter supporting a prosthesis to an entry point of the dissection, wherein the entry point of the dissection is located in a first vessel and the prosthesis comprises a cover and a collapsible anchoring element in communication with the cover;

securing the anchoring element to a second vessel that is in communication with the first vessel;

expanding the cover in the first vessel; and

positioning the cover over at least a portion of the entry point of the dissection;

wherein the cover is configured to reduce blood flow into the entry point of the dissection.

2. The method of claim 1, wherein cover is supported by a collapsible frame and wherein the frame is connected to the anchoring element.

3. The method of claim 2, wherein the frame has an elliptical shape.

4. The method of claim 1, wherein the first or second vessel is the aorta.

5. The method of claim 1, wherein the cover is configured to cover only a portion of an inner perimeter of the first vessel.

6. The method of claim 1, wherein the second vessel is proximal to the entry point of the dissection.

7. The method of claim 1, wherein the first vessel is the subclavian artery.

8. The method of claim 1, wherein the first vessel is the left carotid artery.

9. The method of claim 1, wherein the second vessel is a brachiocephalic artery.

10. The method of claim 1, wherein the cover comprises a protein matrix.

11. The method of claim 10, wherein the protein matrix comprises at least one of collagen, elastin, and mammalian tissue.

12. The method of claim 10, wherein the mammalian tissue comprises tissue harvested from a pericardium or a small intestine submucosa.

13. The method of claim 1, further comprising advancing a support element of the prosthesis through the entry point of the dissection.

14. The method of claim 1, wherein the anchoring element is a stent.

15. A device for treating a vascular dissection, comprising:

an anchoring element; and

a cover supported by the anchoring element;

wherein;

the cover is configured to cover only a portion of a wall of a first vessel over an entry point into the dissection and is configured to at least substantially reduce blood flow into the entry point; and

the anchoring element is configured to be deployed within a second vessel in communication with the first vessel.

16. The device of claim 15, wherein the anchoring element and cover are collapsible into a first collapsed state for positioning within a catheter and are expandable to a second expanded state.

17. The device of claim 15, further comprising a frame configured to support the cover, the frame being attached to the anchoring element.

18. The device of claim 17, wherein the anchoring element, frame, and cover are collapsible into a first collapsed state for positioning within a catheter and expandable to a second expanded state.

19. The device of claim 17, wherein the frame is configured to unfold the cover during deployment of the frame.

20. The device of claim 17, wherein the cover is attached to the frame using sutures or adhesive.

21. The device of claim 17, wherein the frame comprises two interconnected elliptical components.

22. The device of claim 17, wherein the frame comprises a memory material such as Nitinol.

23. The device of claim 15, wherein the cover comprises at least one of a protein matrix, polyester, ePTFE, polyurethane, silk, and animal tissue.

24. The device of claim 23, wherein the protein matrix comprises at least one of mammalian tissue, collagen, elastin, fibrin, polysaccharides such as chitosan or glycosaminoglycans, and a cross-linking agent.

25. The device of claim 24, wherein the cross-linking agents comprise at least one of glutaraldehydes, carbodiimide, tannins, polyphenols, and photo-activated cross-linking agents.

26. The device of claim 24, wherein the mammalian tissue comprises tissue harvested from pericardium, small intestine submucosa, blood vessels, or skin.

27. The device of claim 15, wherein the anchoring element is a stent.

28. The device of claim 15, wherein the anchoring element comprises at least one of a coil, hook, barb, balloon, stent graft, screw, or staple.

29. The device of claim 15, wherein the cover is configured to contact at least a portion of the first vessel.

30. The device of claim 15, further comprising a plurality of supports attached to the anchoring element and configured to support the cover.

31. The device of claim 15, wherein a thickness of the cover is between approximately 0.0001 inches and approximately 0.01 inches.