USE OF SLIM-1 IN THE ASSESSMENT OF HEART FAILURE
First Claim
1. A method for assessing heart failure in an individual comprising the steps ofmeasuring in a sample obtained from the individual a concentration of SLIM-1,optionally measuring in the sample a concentration of a marker selected from the group consisting of NT-proBNP, troponinT, and C-reactive protein (CRP), andassessing heart failure by comparing the concentration of SLIM-1 determined to a concentration of SLIM-1 established in a control sample from a normal population and optionally comparing the concentration of the marker determined to a concentration of the marker established in a control sample from a normal population.
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Abstract
The invention relates to a method for assessing heart failure in vitro comprising the steps of measuring in a sample the concentration of the marker SLIM-1, of optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration determined in for SLIM-1 and the concentration(s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of SLIM-1 as a marker protein in the assessment of heart failure, a marker combination comprising SLIM-1 and a kit for measuring SLIM-1.
24 Citations
4 Claims
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1. A method for assessing heart failure in an individual comprising the steps of
measuring in a sample obtained from the individual a concentration of SLIM-1, optionally measuring in the sample a concentration of a marker selected from the group consisting of NT-proBNP, troponinT, and C-reactive protein (CRP), and assessing heart failure by comparing the concentration of SLIM-1 determined to a concentration of SLIM-1 established in a control sample from a normal population and optionally comparing the concentration of the marker determined to a concentration of the marker established in a control sample from a normal population.
Specification