Contrast Enhanced MRA With Highly Constrained Backprojection Reconstruction Using Phase Contrast Composite Image
First Claim
1. A method for producing a contrast enhanced image of a subject positioned in the field of view (FOV) of a magnetic resonance imaging (MRI) system, the steps comprising:
- a) acquiring with the MRI system a set of phase contrast views of the subject positioned in the FOV;
b) reconstructing a phase contrast composite image from the phase contrast views which indicates a motion value at each composite image pixel of the subject positioned in the FOV;
c) acquiring with the MRI system a set of mask views;
d) acquiring with the MRI system a time frame data set comprised of an undersampled set of contrast enhanced views of the subject positioned in the FOV after the arrival of the contrast agent;
e) repeating step d) to acquire a plurality of time frame data sets during the in flow of contrast agent into the FOV;
f) subtracting mask views from the contrast enhanced views to obtain sparse contrast enhanced views for each time frame; and
g) performing a HYPR reconstruction to produce a contrast enhanced image of the subject for each time frame using both the sparse contrast enhanced views for the time frame and the phase contrast composite image.
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Abstract
Mask projection views are obtained prior to the arrival of a contrast agent during a dynamic contrast enhanced MRA study. After the arrival of the contrast agent, a set of undersampled contrast enhanced projection views are obtained for each of a plurality of time frames. Corresponding mask projection views are subtracted from the contrast enhanced projection views to provide sparse contrast enhanced projection view sets. A phase contrast scan of a region of interest is performed prior to or after the arrival of the contrast agent. The phase contrast image is used as a composite image in a HYPR reconstruction of the sparse projection view sets to produce first pass contrast enhanced images. Iterative HYPR reconstructions can also be performed to remove venous information from the reconstructed images.
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Citations
18 Claims
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1. A method for producing a contrast enhanced image of a subject positioned in the field of view (FOV) of a magnetic resonance imaging (MRI) system, the steps comprising:
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a) acquiring with the MRI system a set of phase contrast views of the subject positioned in the FOV; b) reconstructing a phase contrast composite image from the phase contrast views which indicates a motion value at each composite image pixel of the subject positioned in the FOV; c) acquiring with the MRI system a set of mask views; d) acquiring with the MRI system a time frame data set comprised of an undersampled set of contrast enhanced views of the subject positioned in the FOV after the arrival of the contrast agent; e) repeating step d) to acquire a plurality of time frame data sets during the in flow of contrast agent into the FOV; f) subtracting mask views from the contrast enhanced views to obtain sparse contrast enhanced views for each time frame; and g) performing a HYPR reconstruction to produce a contrast enhanced image of the subject for each time frame using both the sparse contrast enhanced views for the time frame and the phase contrast composite image. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 13, 14, 15, 16, 17, 18)
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10. A method for reconstructing a contrast enhanced magnetic resonance angiographic (CEMRA) image with a magnetic resonance imaging (MRI) system, the steps comprising:
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a) acquiring a composite image of the subject with the MRI system which indicates at least a portion of a vasculature of the subject; b) acquiring a plurality of sets of contrast enhanced views of the subject with the MRI system; and c) reconstructing the CEMRA image using both information in one of the sets of contrast enhanced views and information in the non-contrast enhanced composite image in a HYPR reconstruction.
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Specification