IONTOPHORETIC DEVICE WITH IMPROVED COUNTERELECTRODE
First Claim
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1. An iontophoretic drug delivery device for delivering a drug into the tissue of a wearer, the device comprising:
- a base;
a drug reservoir containing a supply of charged drug ions;
a driving electrode positioned above the drug reservoir;
a counterelectrode positioned below the drug reservoir opposite the driving electrode;
a control circuit including a power source, the control circuit being coupled to the driving electrode and the counterelectrode and operable in a driving mode for applying a potential to the driving electrode of the same polarity as the charge of the charged drug ions and a potential of opposite polarity to the counterelectrode so as to drive the charged drug ions towards the tissue of the wearer.
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Abstract
The present disclosure relates to an iontophoretic device. In one aspect, the device includes a barrier layer between the drug reservoir and wearer. In another aspect, the device includes a counterelectrode opposite the driving electrode relative to the drug reservoir.
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Citations
72 Claims
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1. An iontophoretic drug delivery device for delivering a drug into the tissue of a wearer, the device comprising:
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a base; a drug reservoir containing a supply of charged drug ions; a driving electrode positioned above the drug reservoir; a counterelectrode positioned below the drug reservoir opposite the driving electrode; a control circuit including a power source, the control circuit being coupled to the driving electrode and the counterelectrode and operable in a driving mode for applying a potential to the driving electrode of the same polarity as the charge of the charged drug ions and a potential of opposite polarity to the counterelectrode so as to drive the charged drug ions towards the tissue of the wearer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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35. A method for using an iontophoretic device for delivering a drug into the tissue of a wearer, the device comprising:
- (i) a base, (ii) a driving electrode positioned above the drug reservoir, (iii) a counterelectrode positioned below the drug reservoir opposite the driving electrode, (iv) a control circuit including a power source, the control circuit being coupled to the driving electrode and the counterelectrode, the method comprising operating the device in a driving mode by performing the acts comprising;
applying, with the control circuit, a potential to the driving electrode of the same polarity as the charge of the charged drug ions; and applying, with the control circuit, a potential of opposite polarity to the counterelectrode; wherein the charged drug ions are driven towards the tissue of the wearer. - View Dependent Claims (36, 37, 38, 39)
- (i) a base, (ii) a driving electrode positioned above the drug reservoir, (iii) a counterelectrode positioned below the drug reservoir opposite the driving electrode, (iv) a control circuit including a power source, the control circuit being coupled to the driving electrode and the counterelectrode, the method comprising operating the device in a driving mode by performing the acts comprising;
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40. An iontophoretic drug delivery device for delivering a drug into the tissue of a wearer, the device comprising:
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a base; a drug reservoir comprising a supply of charged drug ions; a driving electrode; a counterelectrode; and a control circuit including a power source, the control circuit being coupled to the driving electrode and the counterelectrode, and being operable to apply a potential of the same polarity as the charge of the charged drug ions to the driving electrode and a potential of opposite polarity to the counterelectrode; the driving electrode and the counterelectrode being (a) coupled with a resistance therebetween such that current is enabled to flow between the driving electrode and the counterelectrode only within the device, and (b) positioned with respect to said drug reservoir such that application of the respective potentials thereto in the driving mode of said control circuit drives the charged drug ions towards the tissue of the wearer. - View Dependent Claims (41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72)
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Specification