TRANSDERMAL PATCH DEVICE

• US 20100286600A1
• Filed: 05/10/2010
• Published: 11/11/2010
• Est. Priority Date: 05/08/2009
• Status: Abandoned Application

• Current Assignee: Bommannan D. Bommi
• Original Assignee: Bommannan D. Bommi
• Inventors: Bommannan, D. Bommi
• Application Number:
  US12/777,037
• Publication Number:
  US 20100286600A1
• Time in Patent Office: Days
• US Class Current: 604/66
• CPC Class Codes: A61K 31/4402 only substituted in position 2, e.g. pheniramine, bisacodyl
• CPC Class Codes: A61K 9/0004 Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
• CPC Class Codes: A61K 9/0021 Intradermal administration, e.g. through microneedle arrays, needleless injectors mechanical aspects A61M
• CPC Class Codes: A61K 9/7084 Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 37/00 Other apparatus for introducing media into the body for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30; Percutany, i.e. introducing medicines into the body by diffusion through the skin salt baths A61H33/04
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/14276 specially adapted for implantation

Abstract

A patch device worn by a user is disclosed that is configured to sense the presence of a harmful substance in the environment and to deliver an antidote to that substance into the user without the intervention of the user. The patch device incorporates a sensing mechanism configured to sense a presence of the harmful substance in the environment surrounding the patch device. On sensing the presence of the harmful substance, the sensor triggers a delivery mechanism, which causes the therapeutic agent to be injected into the user. The therapeutic agent acts to antidote the effects of the harmful substance within the user. The patch device could be used for protection against exposure to substances such as nerve gas and pesticides. The patch could be used to deliver the therapeutic agent either subcutaneously or transdermally.

Claims

1. A patch device for treatment of a user, comprising:

a sensing mechanism configured to sense presence of an analyte in an environment surrounding the user;

a reservoir configured to store a therapeutic agent which counteracts the effects of the analyte; and

a delivery mechanism configured to deliver the therapeutic agent to the user;

wherein the sensing mechanism is further configured to activate the delivery mechanism upon sensing the presence of the analyte, thereby delivering the therapeutic agent to the user in order to counteract the effects of the analyte within the user.

2. The patch device of claim 1, wherein the therapeutic agent is delivered subcutaneously.

3. The patch device of claim 1, wherein the therapeutic agent is delivered transdermally.

4. The patch device of claim 1, wherein the analyte comprises an organophosphate agent.

5. The patch device of claim 1, wherein the therapeutic agent comprises an anti-cholinergic agent or pralidoxime chloride.

6. The patch device of claim 1, wherein the therapeutic agent comprises an anti-allergy agent.

7. The patch device of claim 2, wherein the delivery mechanism is driven by spring force.

8. The patch device of claim 2, wherein the delivery mechanism is driven by gas pressure.

9. The patch device of claim 2, wherein the delivery mechanism is driven by an electrochemical reaction.

10. The patch device of claim 2, wherein the delivery mechanism is driven by a shape memory element.

11. The patch device of claim 1, wherein the sensing mechanism comprises an electrochemical cell.

12. The patch device of claim 1, wherein the sensing mechanism comprises a chemical reaction.

13. The patch device of claim 1, wherein the device is stuck to the skin using an adhesive.

14. The patch device of claim 1, wherein the device is strapped on to the skin of the user.

15. The device of claim 3, wherein the sensing mechanism comprises a chemical change.

16. The device of claim 3, wherein the activation mechanism comprises a chemical change that releases a therapeutic agent.

17. The device of claims 15-16, wherein the sensing and activation steps are the same.

18. A method of treatment of a user comprising:

sensing an analyte in the ambience surrounding a user; and

delivering a therapeutic agent into the user when the analyte is detected;

wherein the delivering is configured to proceed without the intervention of the user.

19. The method of claim 18, wherein the analyte comprises an organophosphate nerve agent.