Methylated Curcumin-Resveratrol Hybrid Molecules for Treating Cancer

• US 20100292512A1
• Filed: 05/13/2010
• Published: 11/18/2010
• Est. Priority Date: 02/12/2008
• Status: Active Grant

• Current Assignee: DePuy Synthes Products LLC (Johnson & Johnson)
• Original Assignee: DePuy Synthes Products LLC (Johnson & Johnson)
• Inventors: DiMauro, Thomas M.
• Granted Patent: US 8,350,093 B2
• Time in Patent Office: Days
• US Class Current: 568/325
• CPC Class Codes: A61K 31/12 Ketones
• CPC Class Codes: A61K 31/336 having three-membered rings, e.g. oxirane, fumagillin
• CPC Class Codes: A61K 9/0043 Nose
• CPC Class Codes: A61P 25/28 for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

Methylated curcumin-methoxystilbene hybrid molecules that have particular use in treating cancer.

Claims

1. 1-methoxyl 3,5-bis(4′

-methoxyl styryl) benzene.

2. 1,3-dimethoxyl 4,6-bis(4′

-methoxyl styryl) benzene.

3. 1-methoxyl 3,5-bis(3′

,4′

-dimethoxyl styryl) benzene.