System and method of measuring changes in arterial volume of a limb segment
First Claim
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1. A method for assessing change in arterial volume of a limb segment of a mammal, said method comprising:
- determining amplitudes of component pulse waves of detected volume pulse waves of a limb segment detected during a baseline period to determine a baseline arterial volume of the limb segment;
determining amplitudes of component pulse waves of detected volume pulse waves of the limb segment detected during a time period after a stimulus has been applied to the mammal to induce a period of change in the arterial volume of the limb segment; and
determining relative change in arterial volume of the limb segment during the time period after the stimulus relative to the arterial volume of the limb segment during the baseline period from the amplitudes of the component pulse waves of the detected volume pulse waves during the baseline and after the stimulus.
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Abstract
A medical diagnostic device performs diagnostics for assessing the ability of the arteries to respond to an increase in blood flow. The medical diagnostic device determines relative changes in arterial volume of the limb segment during a time period after a stimulus relative to the arterial volume of the limb segment during a baseline period using the amplitudes or other portions of the component pulse waves (such as early systolic components) of volume pulse waves during the baseline period and after the stimulus.
111 Citations
58 Claims
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1. A method for assessing change in arterial volume of a limb segment of a mammal, said method comprising:
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determining amplitudes of component pulse waves of detected volume pulse waves of a limb segment detected during a baseline period to determine a baseline arterial volume of the limb segment; determining amplitudes of component pulse waves of detected volume pulse waves of the limb segment detected during a time period after a stimulus has been applied to the mammal to induce a period of change in the arterial volume of the limb segment; and determining relative change in arterial volume of the limb segment during the time period after the stimulus relative to the arterial volume of the limb segment during the baseline period from the amplitudes of the component pulse waves of the detected volume pulse waves during the baseline and after the stimulus. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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28. A diagnostic system for assessing change in arterial volume of a limb segment of a mammal comprising:
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a sensor for detecting volume pulse waves of a limb segment during a baseline period and for detecting volume pulse waves of the limb segment during a period of an after-stimulus change in arterial volume; a processor coupled to the sensor to determine amplitudes of component pulse waves of detected volume pulse waves of the limb segment detected during the baseline period to determine a baseline arterial volume of the limb segment, to determine amplitudes of component pulse waves of detected volume pulse waves of the limb segment detected during a time period after a stimulus has been applied to the mammal to induce a period of change in the arterial volume of the limb segment, and to determine relative change in arterial volume of the limb segment during the time period after the stimulus relative to the arterial volume of the limb during the baseline period from the amplitudes of the component pulse waves of the detected volume pulse waves at baseline and after the stimulus. - View Dependent Claims (29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52)
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53. A machine-readable medium encoded with instructions, that when executed by one or more processors, cause the processor to carry out a process for assessing change in arterial volume of a limb segment of a mammal, the process comprising:
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determining amplitudes of component pulse waves of detected volume pulse waves of a limb segment detected during a baseline period to determine a baseline arterial volume of the limb segment; determining amplitudes of component pulse waves of detected volume pulse waves of the limb segment detected during a time period after a stimulus has been applied to the mammal to induce a period of change in the arterial volume of the limb segment; and determining relative change in arterial volume of the limb segment during the time period after the stimulus relative to the arterial volume of the limb during the baseline period from the amplitudes of the component pulse waves of the detected volume pulse waves at baseline and after the stimulus. - View Dependent Claims (54, 55, 56, 57, 58)
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Specification