TISSUE MODIFICATION DEVICES AND METHODS OF THE SAME

• US 20100292684A1
• Filed: 05/15/2009
• Published: 11/18/2010
• Est. Priority Date: 05/15/2009
• Status: Abandoned Application

• Current Assignee: Axis Surgical Technologies, Inc.
• Original Assignee: Axis Surgical Technologies, Inc.
• Inventors: Cybulski, James S., Schultz, Eric E., Seddiqui, Fred R.
• Application Number:
  US12/467,122
• Publication Number:
  US 20100292684A1
• Time in Patent Office: Days
• US Class Current: 606/33
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 18/042 using additional gas becoming plasma
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2018/00196 reciprocating lengthwise
• CPC Class Codes: A61B 2018/00601 Cutting
• CPC Class Codes: A61B 2018/1407 Loop
• CPC Class Codes: A61B 2218/002 Irrigation
• CPC Class Codes: C08L 2201/12 Shape memory

Abstract

Tissue modification devices are provided. Aspects of the devices include an elongated member having a proximal end and a distal end, an tissue modifier positioned at the distal end, and a linear mechanical actuator configured to linearly translate the RF electrode relative the distal end according to a linear translation waveform. The devices may be configured to operate the tissue modifier according to an operating waveform that is synchronized with the linear translation waveform. Also provided are methods of modifying an internal target tissue of a subject using the tissue modification devices.

Claims

1. A tissue modification device comprising:

an elongated member having a proximal end and a distal end;

a tissue modifier positioned at the distal end; and

a linear mechanical actuator configured to linearly translate the tissue modifier relative the distal end according to a linear translation waveform.

2. The tissue modification device according to claim 1, wherein the device further synchronizes the linear translation waveform with a tissue modifier operating waveform.

3. The tissue modification device according to claim 2, wherein the tissue modifier operating waveform is phase shifted relative to the linear translation waveform.

4. The tissue modification device according to claim 1, wherein the linear translation waveform has a frequency that is 10 Hz or greater.

5. The tissue modification device according to claim 1, wherein the tissue modifier is a RF electrode.

6. The tissue modification device according to claim 5, wherein the RF electrode has an operating waveform that is definable as KHz waveform modulated with an Hz waveform.

7. The tissue modification device according to claim 1, wherein the device comprises a sensor configured to obtain linear translation waveform data.

8. The tissue modification device according to claim 7, wherein the obtained linear translation waveform data is used to synchronize an operating waveform of the tissue modifier with the linear translation waveform.

9. The tissue modification device according to claim 7, wherein the sensor is a sensor selected from the group consisting of an optical encoder, mechanical encoder, optoelectronic sensor, and Hall effect sensor.

10. The tissue modification device according to claim 1, wherein the linear mechanical actuator is selected from a voice-coil, a solenoid and an electric motor.

11. The tissue modification device according to claim 1, wherein the device further comprises a distal end visualization sensor.

12. The tissue modification device according to claim 11, wherein the visualization sensor is selected from a CCD and CMOS sensor.

13. The tissue modification device according to claim 1, wherein the device is configured for distal end steerability.

14. The tissue modification device according to claim 1, wherein the device further comprises a distal end irrigator and aspirator.

15. The tissue modification device according to claim 1, wherein the distal end of the elongated member is dimensioned to access an intervertebral disc.

16. A method of modifying an internal target tissue of a subject, the method comprising:

(a) positioning a tissue modification device comprising;

(i) an elongated member having a proximal end and a distal end;

(ii) a tissue modifier positioned at the distal end; and

(iii) a linear mechanical actuator configured to linearly translate the tissue modifier relative the distal end according to a linear translation waveform;

in operative relationship to the internal target tissue; and

(b) modifying the internal target tissue with the tissue modifier.

17. the method according to claim 16, wherein the tissue modifier comprises a RF electrode and the method comprises delivering RF energy to the internal target tissue in a manner effective to modify the internal target tissue of the subject.

18. The method according to claim 16, wherein the method comprises operating the linear translation actuator at a frequency of 10 Hz or greater.

19. The method according to claim 17, wherein the energy delivered by the tissue modification device is modulated by a modulation waveform that is synchronized with the linear translation waveform to provide the tissue modifier with capability for tissue discrimination based on elastic modulus.

20. The method according to claim 16, wherein the tissue modification device further comprises a visualization element located at the distal end of the elongated member, and the method comprises visualizing the internal target tissue site.

21. The method according to claim 16, wherein the internal target tissue comprises spinal tissue.

22. The method according to claim 16, wherein the method further comprises discriminating between internal tissue types.