MASS SPECTROMETRY APPARATUS AND METHOD USING THE APPARATUS
First Claim
1. A mass spectrometry apparatus comprising:
- a substrate for mass spectrometry that is used in surface-assisted laser desorption/ionization mass spectrometry;
a light irradiation means that irradiates a sample that is in contact with a surface of the substrate for mass spectrometry with measurement light to desorb an analyte contained in the sample from the surface of the substrate for mass spectrometry;
a metal probe that generates near-field light at the leading end thereof by irradiation with the measurement light;
a detector that detects the desorbed analyte; and
an analysis means that performs mass spectrometry on the analyte based on a detection result by the detector, wherein the leading end of the metal probe is arranged in such a manner that the near-field light generated by irradiation with the measurement light is in contact with a measurement light irradiation portion of the sample, and wherein the metal probe is arranged, with respect to the measurement light irradiation portion of the sample, at a position in a different direction from the direction of the detector.
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Accused Products
Abstract
A mass-spectrometry apparatus includes a substrate for mass spectrometry used in surface-assisted laser desorption/ionization mass spectrometry, a light irradiation means that irradiates sample S in contact with a surface of the substrate with measurement light L1 to desorb analyte R in sample S from the surface, a metal probe that generates near-field light at the leading end thereof by irradiation with measurement light L1, a detector that detects desorbed analyte. Ri, and an analysis means that performs mass spectrometry on analyte R based on a detection result by the detector. The leading end of the metal probe is arranged in such a manner that the near-field light generated by irradiation with measurement light L1 is in contact with a measurement light irradiation portion of sample S. The metal probe is arranged, with respect to the measurement light irradiation portion, at a position different from the direction of the detector.
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Citations
16 Claims
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1. A mass spectrometry apparatus comprising:
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a substrate for mass spectrometry that is used in surface-assisted laser desorption/ionization mass spectrometry; a light irradiation means that irradiates a sample that is in contact with a surface of the substrate for mass spectrometry with measurement light to desorb an analyte contained in the sample from the surface of the substrate for mass spectrometry; a metal probe that generates near-field light at the leading end thereof by irradiation with the measurement light; a detector that detects the desorbed analyte; and an analysis means that performs mass spectrometry on the analyte based on a detection result by the detector, wherein the leading end of the metal probe is arranged in such a manner that the near-field light generated by irradiation with the measurement light is in contact with a measurement light irradiation portion of the sample, and wherein the metal probe is arranged, with respect to the measurement light irradiation portion of the sample, at a position in a different direction from the direction of the detector. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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Specification