COMPOSITION FOR THE PREVENTION AND THE TREATMENT OF HELICOBACTER PYLORI INFECTION
First Claim
1. A composition for the prevention of Helicobacter pylori infection, comprising at least 0.128 wt % c catechin and its derivatives;
- at least 0.032 wt % c sialic acid; and
water.
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Accused Products
Abstract
The disclosed item is a composition comprising catechins and sialic acid to provide an effective prevention and treatment for Helicobacter Pylori infection. This composition inhibits growth of Helicobacter pylori, and can increase the antioxidant activity of gastric mucosal cells through reducing the production of O2.−, H2O2 and NO, and decreasing the expression of inducible nitric oxide synthase (iNOS) in cells. The apoptotic damage of stomach caused by Helicobacter pylori was decreased through up-regulation of autophagy to enhance the defensive ability of gastric epithelial cells toward Helicobacter pylori. Therefore the composition can be used in the treatment or prevention on damages caused by Helicobacter pylori infection.
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Citations
16 Claims
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1. A composition for the prevention of Helicobacter pylori infection, comprising at least 0.128 wt % c catechin and its derivatives;
- at least 0.032 wt % c sialic acid; and
water. - View Dependent Claims (2, 3, 4, 5, 6, 7)
- at least 0.032 wt % c sialic acid; and
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8. A composition for the treatment of Helicobacter pylori infection, which comprises from 128 mg/L to 640 mg/L catechin or its derivatives;
- from 32 mg/L to 160 mg/L sialic acid; and
water. - View Dependent Claims (9, 10, 11, 12, 13, 14, 15, 16)
- from 32 mg/L to 160 mg/L sialic acid; and
Specification