SYSTEMS AND METHODS FOR CALCULATING AN AVERAGE ANALYTE CONCENTRATION VALUE

• US 20100299075A1
• Filed: 05/10/2010
• Published: 11/25/2010
• Est. Priority Date: 05/19/2009
• Status: Abandoned Application

• Current Assignee: Ascensia Diabetes Care Holdings AG (PHC Holdings Corporation)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Li, Qiong, Pardo, Scott, Telson, Stanley A.
• Application Number:
  US12/777,199
• Publication Number:
  US 20100299075A1
• Time in Patent Office: Days
• US Class Current: 702/19
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

Embodiments provide methods and systems wherein analyte concentration readings taken over a first period of time are collected and processed to determine one or more analyte concentration averages. The methods include collecting samples with a measurement system (e.g., a Blood Glucose Meter) over a first period of time, dividing the first period of time into smaller time increments, and calculating an average analyte concentration based on first sub-averages obtained from each of the smaller time increments. Systems for carrying out the analyte concentration averages are described, as are other aspects.

Claims

1. A method to determine an average analyte value, comprising:

measuring a plurality of analyte concentration readings over a time period with an analyte measurement device;

selecting a first period of time within the time period;

dividing the first period of time into a plurality of smaller time increments each including at least three analyte concentration readings;

averaging the analyte concentration readings within the plurality of smaller time increments to calculate first sub-averages;

averaging two or more of the first sub-averages to calculate at least one second sub-average; and

displaying at least one average selected from the group of;

an average based on the first sub-averages,

an average based on the at least one second sub-average, and

an overall analyte average over the first period of time based on the at least one second sub-average.

2. The method of claim 1 further comprising downloading the plurality of analyte concentration readings to a host device.

3. The method of claim 1 wherein each of the plurality of smaller time increments are substantially equal length time increments.

4. The method of claim 1 further comprising not using in the calculation of the first sub-averages any analyte concentration reading which is missing.

5. The method of claim 1 further comprising not using in the calculation of the first sub-averages any analyte concentration reading which is determined to be an improper analyte reading.

6. The method of claim 5 wherein the improper analyte reading is determined to be improper by comparing the improper analyte reading to at least one characteristic of at least one previously-obtained analyte reading.

7. The method of claim 1 wherein the at least one second sub-average is over a sub-increment of time smaller than the first period of time.

8. The method of claim 1 wherein the analyte concentration readings are unequally spaced in time over the first period of time.

9. The method of claim 1 wherein the analyte measurement system is one system selected from a group consisting of a BGM, a CGM, CGM/Pump combination.

10. The method of claim 1 wherein the smaller time increment is one time increment selected from the group consisting of 15 minutes, a half hour, an hour, 24 hours, a week, and a month.

11. The method of claim 1 wherein the analyte concentration readings comprise glucose concentration readings.

12. The method of claim 1 wherein the overall analyte average is based at least in part on an arithmetic average of the at least one second sub-average and at least one other second sub-average.

13. The method of claim 1 wherein plurality of smaller time increments include between 3 and 100 analyte concentration readings.

14. The method of claim 1 wherein all second sub-averages over the first period of time are averaged.

15. The method of claim 1 wherein the at least one second sub-average is averaged with at least one other second sub-average to produce a third sub-average.

16. The method of claim 1 wherein all second sub-averages are averaged to produce an overall second sub-average.

17. The method of claim 1 wherein the overall analyte average over the first period of time is based at least in part on an average of third sub-averages.

18. The method of claim 17 wherein the overall analyte average over the first period of time is based on averaging sub-averages beyond the third sub-average.

19. The method of claim 1 wherein at least some of the plurality of analyte concentration readings within the plurality of smaller time increments are discarded.

20. The method of claim 1 wherein a number (m) of the plurality of smaller time increments is selected such that each of the plurality of smaller time increments includes at least a number (k) of the analyte concentration readings wherein m>

5 and k>

5.

21. A method to determine an average analyte value, comprising:

measuring a plurality of analyte concentration readings with an analyte measurement system over a time period;

downloading the plurality of analyte concentration readings to a host device;

selecting a first period of time within the time period,

dividing the first period of time into a plurality of smaller time increments of substantially equal lengths;

averaging the analyte concentration readings for each of the smaller time increments to determine first sub-averages for each of the smaller time increments;

averaging the first sub-averages to arrive at a plurality of second sub-averages;

averaging the second sub-averages to arrive at at least one third sub-average; and

displaying on the host device at least one average selected from the group of;

the first sub-averages,

the second sub-averages,

the at least one third sub-average, and

an overall analyte average over the first period of time.

22. A system adapted to calculate an average analyte value, comprising:

a measurement system adapted to obtain a plurality of analyte concentration readings;

a host device adapted to receive at least some of the plurality of analyte concentration readings, the host device including;

a processor adapted to calculate an analyte concentration average over a selected first period of time wherein a plurality of analyte readings over the first period of time are stored in memory and the processor calculates an analyte concentration average based on;

dividing the first period of time into a plurality of smaller time increments, each smaller time increment including at least three analyte concentration readings,

averaging the analyte concentration readings for each of the smaller time increments to determine a first sub-average for each of the smaller time increments, and

averaging at least some of the first sub-averages to arrive at at least one second sub-average.