Analysis Tool, Analyzer, Sample Shortage Detection Method, and Sample Analysis Method

• US 20100300898A1
• Filed: 10/31/2008
• Published: 12/02/2010
• Est. Priority Date: 10/31/2007
• Status: Abandoned Application

• Current Assignee: ARKRAY, Inc
• Original Assignee: ARKRAY, Inc
• Inventors: Sato, Yoshiharu, Fujii, Tomohiro
• Application Number:
  US12/740,865
• Publication Number:
  US 20100300898A1
• Time in Patent Office: Days
• US Class Current: 205/792
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52

Abstract

There is provided an analysis tool having a plurality of electrodes formed on a substrate. The plurality electrodes include two or more first electrodes having working electrodes and one or more second electrodes having counter electrodes. The analysis tool may also additionally have a flow channel for transferring a sample. The electrodes are preferably disposed so that the working electrodes and the counter electrodes have a symmetrical positional relationship with each other in a transferring direction of the sample in the flow channel.

Claims

1. An analysis tool comprising:

a substrate; and

a plurality of electrodes formed on the substrate,

wherein the plurality of electrodes comprises at least two first electrodes each having a working electrode and at least one second electrode having a counter electrode.

2. The analysis tool of claim 1 further comprising a flow channel for transferring a sample, wherein the plurality of electrodes are arranged so that the working electrode and the counter electrode have a symmetrical positional relationship in a movement direction of the sample in the flow channel.

3. The analysis tool of claim 2, wherein the number of the at least one second electrode is equal to the number of the at least two first electrodes.

4. The analysis tool of claim 3, wherein the plurality of electrodes are arranged side by side in the order of:

a counter electrode, a working electrode, another working electrode, and another counter electrode, with respect to the movement direction.

5. The analysis tool of claim 3, wherein the plurality of electrodes are arranged side by side in the order of:

a working electrode, a counter electrode, another counter electrode, and another working electrode, with respect to the movement direction.

6. The analysis tool of claim 2, wherein the plurality of electrodes are arranged side by side in the order of:

a working electrode, a counter electrode, and another working electrode, with respect to the movement direction.

7. The analysis tool of claim 1, wherein each of the working electrodes of the at least two first electrodes has substantially the same surface area.

8. An analyzer for performing analysis of a sample using an analysis tool, the analysis tool having first and second working electrodes and at least one counter electrode, the analyzer comprising:

an electric current measurement component that measures a response electric current when a voltage is applied between the first and second working electrodes and the at least one counter electrode;

a detection component that detects a shortage of the sample supplied to the analysis tool by comparing a first response electric current, obtained when a voltage is applied between the first working electrode and the counter electrode, with a second response electric current, obtained when a voltage is applied between the second working electrode and the counter electrode; and

an analysis component that performs analysis of the sample based on at least one of the first or second response electric currents.

9. A method of detecting whether or not there is a shortage of a sample supplied to an analysis tool when the sample is analyzed using the analysis tool, the analysis tool having first and second working electrodes and at least one counter electrode, the method of detecting comprising:

comparing a first response electric current, obtained when a voltage is applied between the first working electrode and the at least one counter electrode, with a second response electric current, obtained when a voltage is applied between the second working electrode and the at least one counter electrode; and

determining whether or not there is a shortage of the amount of the sample supplied to the analysis tool.

10. The method of claim 9, wherein it is determined that there is a shortage of the sample supplied to the analysis tool when a difference between the first and second response electric currents is not within a predetermined range.

11. The method of claim 9, wherein the at least one counter electrode comprises a first counter electrode and a second counter electrode, the first response electric current being measured when a voltage is applied between the first working electrode and the first counter electrode, and the second response electric current being measured when a voltage is applied between the second working electrode and the second counter electrode.

12. The method of claim 9, wherein the analysis tool has a flow channel for transferring the sample, and the first and second working electrodes and the at least one counter electrode are arranged symmetrically in a movement direction of the sample.

13. The method of claim 9, wherein each of the first and second working electrodes has substantially the same area.

14. A method of analyzing a sample using an analysis tool, the analysis tool having first and second working electrodes and at least one counter electrode, the method comprising:

detecting a shortage of the sample, which is supplied to the analysis tool, by comparing a first response electric current, obtained when a voltage is applied between the first working electrode and the at least one counter electrodes, with a second response electric current, obtained when a voltage is applied between the second working electrode and the at least one counter electrode; and

analyzing the sample is analyzed based on at least one of the first or second response electric currents.