×

CELL ROLLING SEPARATION

  • US 20100304485A1
  • Filed: 09/29/2008
  • Published: 12/02/2010
  • Est. Priority Date: 09/27/2007
  • Status: Active Grant
First Claim
Patent Images

1. A method comprising steps of:

  • providing a surface that is at least partially coated with an ordered layer of cell adhesion molecules, wherein the surface comprises at least one edge between an area coated with the ordered layer and another area that is not coated with the ordered layer; and

    flowing a population of cells across the surface in a direction which forms a non-zero angle α

    s with the at least one edge, wherein at least one cell in the population of cells comprises a surface moiety that is recognized by the cell adhesion molecules and wherein the at least one cell rolls for a period of time in a direction that is α

    s to the direction of flow as a result of interacting with at least a portion of the at least one edge.

View all claims
  • 4 Assignments
Timeline View
Assignment View
    ×
    ×