Electrochemical Analyte Sensor
First Claim
1. An in vivo glucose sensor, comprising:
- one or more working electrodes;
a sensing layer proximate to at least one of the one or more working electrodes; and
a mass transport limiting layer proximate to at least one of the one or more working electrodes;
wherein the flexibility of the sensor is varied along a continuum of the sensor.
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Accused Products
Abstract
An electrochemical analyte sensor formed using conductive traces on a substrate can be used for determining and/or monitoring a level of analyte in in vitro or in vivo analyte-containing fluids. For example, an implantable sensor may be used for the continuous or automatic monitoring of a level of an analyte, such as glucose, lactate, or oxygen, in a patient. The electrochemical analyte sensor includes a substrate and conductive material disposed on the substrate, the conductive material forming a working electrode. In some sensors, the conductive material is disposed in recessed channels formed in a surface of the sensor. An electron transfer agent and/or catalyst may be provided to facilitate the electrolysis of the analyte or of a second compound whose level depends on the level of the analyte. A potential is formed between the working electrode and a reference electrode or counter/reference electrode and the resulting current is a function of the concentration of the analyte in the body fluid.
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Citations
21 Claims
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1. An in vivo glucose sensor, comprising:
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one or more working electrodes; a sensing layer proximate to at least one of the one or more working electrodes; and a mass transport limiting layer proximate to at least one of the one or more working electrodes; wherein the flexibility of the sensor is varied along a continuum of the sensor. - View Dependent Claims (2, 3, 4, 5, 6)
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7. An in vivo glucose sensor, comprising:
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one or more working electrodes; and a sensing layer proximate to at least one of the one or more working electrodes; wherein the length of the sensor is between 0.3 cm and 5 cm, and the flexibility of the sensor is varied along a continuum of the sensor. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14)
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15. An in vivo glucose sensor, comprising:
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a substrate having a thickness of 50 μ
m to 500 μ
m;one or more working electrodes disposed on the substrate; and a sensing layer proximate to at least one of the one or more working electrodes; wherein the flexibility of the sensor is varied along a continuum of the sensor; and
furtherwherein the sensor has a period of operation of at least one week. - View Dependent Claims (16, 17, 18, 19, 20, 21)
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Specification