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Optimized Proteins that Target Ep-CAM

  • US 20100311954A1
  • Filed: 03/15/2010
  • Published: 12/09/2010
  • Est. Priority Date: 03/01/2002
  • Status: Abandoned Application
First Claim
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1. A variant anti-Ep-CAM antibody comprising a variant human Fc domain, said variant human Fc domain comprising at least one modification that alters binding of said antibody to an Fc receptor compared to a parent human Fc domain.

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