FLEXIBLE POUCH AND CARTRIDGE WITH FLUIDIC CIRCUITS
First Claim
Patent Images
1. A flexible fluid analysis device comprising:
- (i) at least one reservoir in fluid communication with;
(ii) a first fluid channel, which is also in fluid communication with;
(iii) a mixing chamber, the mixing chamber also in fluid communication with;
(iv) a second fluid channel; and
(v) an outlet for draining fluids from the mixing chamber, the outlet in fluid communication with the second fluid channel;
wherein the flexible fluid analysis device comprises a unitary body.
2 Assignments
0 Petitions
Accused Products
Abstract
Flexible pouch and flexible cartridge devices for fluid sample processing, related methods of making and using, related manufacturing systems and related instrumentation systems are described. Flexible pouches provide broad advantage in a wide variety of fields by overcoming the need for complex instrumentation, dedicated devices, and relatively high cost in conventional fluid sample devices. Flexible cartridge devices are particularly advantageous in control of fluid handling, rapid adaptation to a number of configurations by the end user, multiple uses for a single configuration, and in cost and ease of manufacture.
102 Citations
30 Claims
-
1. A flexible fluid analysis device comprising:
-
(i) at least one reservoir in fluid communication with; (ii) a first fluid channel, which is also in fluid communication with; (iii) a mixing chamber, the mixing chamber also in fluid communication with; (iv) a second fluid channel; and (v) an outlet for draining fluids from the mixing chamber, the outlet in fluid communication with the second fluid channel; wherein the flexible fluid analysis device comprises a unitary body. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
-
-
14. An automated actuation instrumentation system configured to manipulate a flexible fluid analysis device in order to carry out a procedure for isolation or identification of a target species in a fluid sample, wherein the flexible fluid analysis device is a flexible pouch or a flexible cartridge and comprises:
-
(i) at least one reservoir in fluid communication with; (ii) a first fluid channel, which is also in fluid communication with; (iii) a mixing chamber, the mixing chamber also in fluid communication with; (iv) a second fluid channel; and (v) an outlet for draining fluids from the mixing chamber, the outlet in fluid communication with the second fluid channel. - View Dependent Claims (15, 16, 17)
-
-
18. A flexible pouch device adapted for isolating a target species pre-labeled with a selectable binding agent from a fluid sample, the flexible pouch device including:
-
a pouch body including a fluidic circuit including at least one reservoir and at least one fluidic channel, the fluidic circuit adapted for flow of the fluid sample through the fluidic circuit; separation of the target species pre-labeled with the selectable binding agent from the fluid sample; and collection of the separated target species within the fluidic circuit. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27)
-
-
28. An apparatus for creating a fluidic circuit from a featureless bag, the apparatus comprising:
-
(i) one or more molds and/or clamps which create the fluidic circuit upon engagement with the featureless bag; and (ii) one or more actuators for manipulating the fluidic circuit, the manipulation comprising valving and pumping a fluid sample within the fluidic circuit. - View Dependent Claims (29)
-
-
30. A process for manufacturing a plurality of flexible pouch devices from one or more sheets of polymeric material, the method comprising:
-
(i) arranging the one or more sheets of polymeric material so that there is an overlapping region of the polymeric material; and (ii) applying opposing plates with premilled molds to the overlapping region in order to form at least one flexible pouch device of the plurality of flexible pouch devices; wherein each flexible pouch device comprises at least one fluidic circuit including at least one reservoir in fluid communication with another reservoir.
-
Specification