Tissue Oxygenation Monitoring in Heart Failure
First Claim
1. A medical device for monitoring delivery of a therapy, comprising:
- a sensor sensing an optical sensor signal corresponding to light attenuation by a volume of body tissue of a patient;
a therapy delivery module to deliver the therapy; and
a processor configured to compute a first tissue oxygenation measurement from the optical sensor signal prior to initiating delivery of the therapy, compute a second tissue oxygenation measurement from the optical sensor signal subsequent to initiating delivery of the therapy, compare the first and the second tissue oxygenation measurements, and determine whether the delivered therapy was successful in response to the first tissue oxygenation measurement and the second tissue oxygenation measurement.
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Abstract
A medical device system and associated method are used for monitoring a heart failure patient. A medical device for monitoring delivery of a therapy includes a sensor sensing an optical sensor signal corresponding to light attenuation by a volume of body tissue of a patient, a therapy delivery module to deliver a therapy, and a processor configured to compute a first tissue oxygenation measurement from the optical sensor signal prior to initiating delivery of the therapy, compute a second tissue oxygenation measurement from the optical sensor signal subsequent to initiating delivery of the therapy, compare the first and the second tissue oxygenation measurements, and determine whether the delivered therapy was successful in response to the first tissue oxygenation measurement and the second tissue oxygenation measurement.
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Citations
24 Claims
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1. A medical device for monitoring delivery of a therapy, comprising:
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a sensor sensing an optical sensor signal corresponding to light attenuation by a volume of body tissue of a patient; a therapy delivery module to deliver the therapy; and a processor configured to compute a first tissue oxygenation measurement from the optical sensor signal prior to initiating delivery of the therapy, compute a second tissue oxygenation measurement from the optical sensor signal subsequent to initiating delivery of the therapy, compare the first and the second tissue oxygenation measurements, and determine whether the delivered therapy was successful in response to the first tissue oxygenation measurement and the second tissue oxygenation measurement. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. The device of claim 8, wherein computing the first tissue oxygenation measurement and the second tissue oxygenation measurement further comprises computing a tissue oxygenation index as a function of the tissue oxygen saturation and the total hemoglobin volume fraction.
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9. A method for monitoring delivery of a therapy in a medical device, comprising;
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sensing an optical sensor signal corresponding to light attenuation by a volume of body tissue of a patient; initiating delivery of the therapy; computing a first tissue oxygenation measurement from the optical sensor signal prior to initiating deliver of the therapy; computing a second tissue oxygenation measurement from the optical sensor signal subsequent to initiating delivery of the therapy; comparing the first and the second tissue oxygenation measurements; and determining whether the therapy was successful in response to the first tissue oxygenation measurement and the second tissue oxygenation measurement. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16)
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17. A computer readable medium having computer executable instructions for performing a method comprising:
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sensing an activity sensor signal; detecting a change in activity level of the patient from the activity sensor signal; computing a tissue oxygenation measurement in response to detecting the change in activity level; detecting a decrease in tissue oxygenation in response to the tissue oxygenation measurement computed in response to detecting the change in activity level; and adjusting a parameter controlling delivery of the therapy in response to detecting the decreased tissue oxygenation. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24)
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Specification