DELIVERY AND ADMINISTRATION OF COMPOSITIONS USING INTERVENTIONAL CATHETERS
First Claim
Patent Images
1. A system for removing unwanted material from a body lumen comprising:
- (a) a catheter;
(b) an operating head positioned at or near a distal end of the catheter;
(c) at least one infusion port provided near a distal end of the catheter and in proximity to the operating head; and
(d) at least one tissue penetration member provided in conjunction with the operating head in proximity to the infusion port,wherein the at least one tissue penetration member is adapted to contact tissue within a body lumen to promote uptake of a composition infused through the at lest one infusion port.
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Accused Products
Abstract
Systems and methods for delivery of therapeutic and/or diagnostic compositions to an interventional site having diseased or newly treated tissue are provided. Integrated interventional catheter systems incorporating surfaces coated with a therapeutic composition, or tissue penetration members for scoring or disrupting tissue prior to or during administration of a therapeutic composition are provided. Infusion of therapeutic composition(s) may also be provided.
316 Citations
18 Claims
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1. A system for removing unwanted material from a body lumen comprising:
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(a) a catheter; (b) an operating head positioned at or near a distal end of the catheter; (c) at least one infusion port provided near a distal end of the catheter and in proximity to the operating head; and (d) at least one tissue penetration member provided in conjunction with the operating head in proximity to the infusion port, wherein the at least one tissue penetration member is adapted to contact tissue within a body lumen to promote uptake of a composition infused through the at lest one infusion port. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for administering a therapeutic and/or diagnostic composition to an internal lumen or cavity prior to, during or following an interventional procedure, comprising:
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(a) delivering the working head of an interventional catheter to the site of an interventional procedure; (b) operating the working head to at least partially displace or remove an obstruction from an internal lumen or cavity; (c) contacting tissue penetrating structures mounted on a component of the interventional catheter to tissue remaining at the site of the interventional procedure following operation of the working head; and (d) administering a therapeutic and/or diagnostic composition to the site of the interventional procedure during or following contacting of the tissue penetrating structures to the tissue at the site of the interventional procedure. - View Dependent Claims (13, 14, 15, 16, 17, 18)
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Specification