MEDICAL DEVICE ENCAPSULATED WITHIN BONDED DIES

• US 20100324614A1
• Filed: 06/18/2009
• Published: 12/23/2010
• Est. Priority Date: 06/18/2009
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: O'Brien, Richard J., Batchelder, Geoffrey DeWitt, Danzl, Ralph, Mueller, Tyler J., Mattes, Michael F., Schugt, Michael A., Norgaard, Clark B., Gerrish, Paul F., Malin, Anna J.
• Granted Patent: US 8,172,760 B2
• Time in Patent Office: Days
• US Class Current: 607/6
• CPC Class Codes: A61N 1/375 Constructional arrangements, e.g. casings
• CPC Class Codes: A61N 1/37512 Pacemakers
• CPC Class Codes: A61N 1/3758 Packaging of the components within the casing

Abstract

An implantable medical system includes a first die substrate with a first outer surface. The system also includes a second die substrate with a second outer surface. Furthermore, the system includes a medical device with a first portion that is mounted to the first die substrate and a second portion that is mounted to the second die substrate. The first and second die substrates are fixed to each other and substantially hermetically sealed to each other. Also, the medical device is substantially encapsulated between the first and second die substrates. The first portion is electrically connected to the second portion. Moreover, the first and second outer surfaces of the first and second die substrates are directly exposed to a biological material.

Claims

1. An implantable medical system comprising:

a first die substrate with a first outer surface;

a second die substrate with a second outer surface; and

a medical device with a first portion that is mounted to the first die substrate and a second portion that is mounted to the second die substrate, the first and second die substrates being fixed to each other and substantially hermetically sealed to each other, the medical device substantially encapsulated between the first and second die substrates, the first portion being electrically connected to the second portion, the first and second outer surfaces of the first and second die substrates being directly exposed to a biological material.

2. The implantable medical system of claim 1, wherein the first and second die substrates cooperate to define a cavity that is enclosed and substantially hermetically sealed between the first and second die substrates.

3. The implantable medical system of claim 2, wherein the first die substrate includes a first mating surface with an inner recess, wherein the second die substrate includes a second mating surface, and wherein the first and second mating surfaces are fixed to each other to substantially hermetically seal the inner recess and to define the cavity.

4. The implantable medical system of claim 2, wherein the first portion of the medical device includes a first sensor electrode that is disposed on an interior surface of the cavity on the first die substrate, and wherein the second portion of the medical device includes a second sensor electrode that is disposed on an interior surface of the cavity on the second die substrate, the first and second sensor electrodes cooperating with each other to detect a characteristic of the biological material.

5. The implantable medical system of claim 4, wherein at least one of the first and second die substrates includes a diaphragm that is deflectable by the biological material to move at least one of the first and second sensor electrodes relative to the other.

6. The implantable medical system of claim 5, wherein the medical device is a pressure sensor that detects a pressure of the biological material based on deflection of the diaphragm by the biological material.

7. The implantable medical system of claim 1, wherein the first outer surface includes an outer recess, and further comprising an outer electrode disposed within the outer recess, the outer electrode in electrical communication with the medical device.

8. The implantable medical system of claim 1, wherein the first and second die substrates are bonded directly together non-adhesively.

9. The implantable medical system of claim 1, wherein the first and second die substrates each include a plurality of layers, and wherein the first portion and the second portion are each at least partially embedded within the respective plurality of layers.

10. The implantable medical system of claim 1, further comprising a cardiac device and a lead, the lead being coupled to the first and second die substrates and being in electrical communication with the medical device, the medical device in communication with the cardiac device via the lead.

11. A method of using a medical system comprising:

forming a first portion of a medical device on a first die substrate, the first die substrate having a first outer surface;

forming a second portion of the medical device on a second die substrate, the second die substrate having a second outer surface;

fixing the first die substrate to the second die substrate to substantially hermetically seal the first die substrate to the second die substrate, to electrically connect the first and second portions of the medical device together, and to encapsulate the medical device therebetween; and

implanting the medical system within a patient to directly expose the first and second outer surfaces to a biological material, the first and second die substrates acting as a barrier between the biological material and the medical device.

12. The method of claim 11, further comprising detecting a characteristic of the biological material with the medical device.

13. The method of claim 12, wherein detecting a characteristic of the biological material comprises detecting a pressure of the biological material.

14. The method of claim 11, wherein fixing the first die substrate to the second die substrate comprises defining a substantially hermetically sealed cavity between the first die substrate and the second die substrate.

15. The method of claim 14, wherein fixing the first die substrate to the second die substrate comprises mating a first mating surface of the first die substrate to a second mating surface of the second die substrate, the first mating surface including an inner recess, and wherein mating the first mating surface to the second mating surface comprises substantially hermetically sealing the inner recess to define the cavity.

16. The method of claim 14, further comprising disposing a first sensor electrode on an interior surface of the cavity on the first die substrate, and further comprising disposing a second sensor electrode on an interior surface of the cavity on the second die substrate, the first and second sensor electrodes cooperating with each other to detect a characteristic of the biological material.

17. The method of claim 16, wherein detecting the characteristic of the biological material comprises detecting an amount of deflection of a diaphragm included on at least one of the first and second die substrates based on a distance between the first and second sensor electrodes.

18. The method of claim 11, further comprising forming an outer recess on the first outer surface, disposing an outer electrode within the outer recess, and electrically connecting the outer electrode to the medical device.

19. The method of claim 11, wherein fixing the first die substrate to the second die substrate comprises bonding the first die substrate directly to the second die substrate non-adhesively.

20. The method of claim 19, further comprising applying at least one of heat and pressure to bond the first die substrate directly to the second die substrate.

21. The method of claim 11, wherein forming the first portion of the medical device on the first die substrate comprises embedding at least part of the first portion within a plurality of layers of the first die substrate, and wherein forming the second portion of the medical device on the second die substrate comprises embedding at least part of the second portion within a plurality of layers of the second die substrate.

22. The method of claim 11, further comprising implanting a cardiac device and a lead, the lead being coupled to the first and second die substrates and being in electrical communication with the medical device, and further comprising transmitting a signal between the medical device and the cardiac device via the lead.

23. An implantable medical system comprising:

a cardiac device;

a lead; and

a medical device assembly that includes;

a first die substrate with a first outer surface and a first mating surface, the first outer surface having an outer recess, and the first mating surface having an inner recess;

a second die substrate with a second outer surface and a second mating surface; and

a medical device with a first portion that is mounted to the first die substrate and a second portion that is mounted to the second die substrate, the first portion including an outer electrode that is disposed within the outer recess and that is electrically connected to the lead, the first and second mating surfaces being directly bonded to each other non-adhesively to substantially hermetically seal the inner recess and to define a cavity therebetween, the first and second portions being electrically connected to each other, the first and second die substrates encapsulating the medical device therebetween, the first portion including a first pressure electrode that is disposed on an inner surface of the cavity on the first die substrate, the second portion including a second pressure electrode that is disposed on an inner surface of the cavity on the second die substrate, at least one of the first and second die substrates including a diaphragm, the first and second pressure sensor electrodes cooperating to detect an amount of deflection of the diaphragm to detect a blood pressure and sending a corresponding signal to the cardiac device via the lead, the first and second outer surfaces of the first and second die substrates being directly exposed to blood and acting as a barrier between the blood and the medical device.