Method and Systems for Controlling Ultrafiltration Using Central Venous Pressure Measurements

• US 20100331754A1
• Filed: 09/03/2010
• Published: 12/30/2010
• Est. Priority Date: 09/28/2007
• Status: Abandoned Application

• Current Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Original Assignee: Fresenius Medical Care Holdings Incorporated (Fresenius SE & Co. KGaA)
• Inventors: Gura, Victor, Braig, James R., Fulkerson, Barry N.
• Application Number:
  US12/875,888
• Publication Number:
  US 20100331754A1
• Time in Patent Office: Days
• US Class Current: 604/6.09
• CPC Class Codes: A61B 5/02152 specially adapted for venous pressure
• CPC Class Codes: A61B 5/412 Detecting or monitoring sepsis
• CPC Class Codes: A61M 1/3653 Interfaces between patient blood circulation and extra-corporal blood circuit
• CPC Class Codes: A61M 1/3659 Cannulae pertaining to extracorporeal circulation
• CPC Class Codes: A61M 1/3661 for haemodialysis
• CPC Class Codes: A61M 2230/30 Blood pressure A61M2230/04 takes precedence
• CPC Class Codes: B01D 61/22 Controlling or regulating
• CPC Class Codes: B01D 61/32 Controlling or regulating

Abstract

The volume of fluid removed from a patient during ultrafiltration is controlled automatically on the basis of central venous pressure (CVP) measurements. In one embodiment, a central venous catheter (CVC) is used for accessing blood during dialysis. A sensor located at the tip of the catheter or inside the dialysis machine is used to periodically measure CVP. CVP feedback data helps prevent the excessive removal of fluids from the patient.

Claims

1. A method for regulating a volume of fluid removed from a patient during renal dialysis, the method comprising:

a. Placing a catheter into a central vena cava of the patient;

b. Connecting said catheter to a blood circuit of a dialysis system, wherein said blood circuit comprises a pressure sensor and a dialyzer and wherein said pressure sensor is upstream from said dialyzer;

c. Operating said dialysis system to circulate blood of said patient through said blood circuit;

d. Measuring a pressure value indicative of a central venous pressure of said patient using said pressure sensor; and

e. Adjusting an ultrafiltration rate based on the measured pressure value.

2. The method of claim 1 wherein said measurement of the pressure value occurs based on a preset frequency.

3. The method of claim 2 further comprising the step of setting said frequency prior to operating said dialysis system.

4. The method of claim 1 further comprising the step of setting an acceptable range of pressure values prior to operating said dialysis system.

5. The method of claim 4, further comprising the step of discontinuing ultrafiltration when said measured pressure value is outside said acceptable range.

6. The method of claim 1 further comprising the step of setting a total volume of fluid to be removed from said patient prior to operating said dialysis system.

7. The method of claim 1, further comprising the step of stopping said circulation of blood through the blood circuit when the pressure value is measured.

8. The method of claim 1, wherein said blood circuit comprises a blood access line and a blood return line and wherein said catheter is connected to both said blood access line and said blood return line.

9. The method of claim 8, wherein said catheter is a dual lumen catheter.

10. The method of claim 8, wherein said catheter has a proximal end and a distal end and wherein said distal end is connected to said blood access line and said proximal end is connected to said blood return line.

20. The method of claim 1, wherein said catheter has a proximal end and wherein the sensor is located at said proximal end.

11. A method for regulating a volume of fluid removed from a patient during renal dialysis, the method comprising:

a. Placing a catheter into a central vena cava of the patient, wherein said catheter comprises a sensor;

b. Connecting said catheter to a blood circuit of a dialysis system;

c. Operating said dialysis system to circulate blood of said patient through said blood circuit;

d. Measuring a pressure value indicative of a central venous pressure of said patient using said sensor; and

e. Adjusting an ultrafiltration rate based on the measured pressure value.

12. The method of claim 11 wherein said measurement of the pressure value occurs based on a preset frequency.

13. The method of claim 12 further comprising the step of setting said frequency prior to operating said dialysis system.

14. The method of claim 11 further comprising the step of setting an acceptable range of pressure values prior to operating said dialysis system.

15. The method of claim 14, further comprising the step of discontinuing ultrafiltration when said measured pressure value is outside said acceptable range.

16. The method of claim 11 further comprising the step of setting a total volume of fluid to be removed from said patient prior to operating said dialysis system.

17. The method of claim 11, further comprising the step of stopping said circulation of blood through the blood circuit when the pressure value is measured.

18. The method of claim 11, wherein said blood circuit comprises a blood access line and a blood return line and wherein said catheter is connected to both said blood access line and said blood return line.

19. The method of claim 18, wherein said catheter has a proximal end and a distal end and wherein said distal end is connected to said blood access line and said proximal end is connected to said blood return line.