METHOD OF ANALYZING BIOLOGICAL COMPONENT, BIOLOGICAL COMPONENT ANALYZER, REACTION CARTRIDGE OF BIOLOGICAL COMPONENT ANALYZER AND EXTRACTION CARTRIDGE OF BIOLOGICAL COMPONENT ANALYZER

• US 20110004086A1
• Filed: 09/17/2010
• Published: 01/06/2011
• Est. Priority Date: 03/19/2008
• Status: Abandoned Application

• Current Assignee: Sysmex Corporation
• Original Assignee: Sysmex Corporation
• Inventors: Asakura, Yoshihiro
• Application Number:
  US12/884,750
• Publication Number:
  US 20110004086A1
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150091 by electricity
• CPC Class Codes: A61B 5/150229 Pumps for assisting the blood sampling
• CPC Class Codes: A61B 5/150343 Collection vessels for collecting blood samples from the skin surface, e.g. test tubes, cuvettes sampling from within body cavities A61B5/150015, A61B5/150045
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150748 Having means for aiding positioning of the piercing device at a location where the body is to be pierced means for aiding positioning of devices for bringing media into the body A61M5/427, locating blood vessels A61B5/489
• CPC Class Codes: A61B 5/150984 Microneedles or microblades
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/1519 comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61B 5/6824 Arm or wrist
• CPC Class Codes: A61B 5/685 Microneedles

Abstract

This method of analyzing a biological component includes steps of arranging an extraction medium holding device on the skin of a subject, extracting an extract from the subject, attaching a reaction cartridge configured to be detachable on an extraction medium holding part of the extraction medium holding device and to be capable of transferring an extraction medium to a reaction part to the extraction medium holding part of the extraction medium holding device arranged on the skin, and transferring the extraction medium held in the extraction medium holding part to the reaction part.

Claims

1. A method of analyzing a biological component comprising steps of:

arranging an extraction medium holding device comprising an extraction medium holding part configured to be capable of holding an extraction medium for holding an extract extracted from a subject on the skin of the subject;

extracting said extract from the subject to said extraction medium held in said extraction medium holding part;

attaching a reaction cartridge comprising a reaction part allowing said extract to cause a prescribed reaction, configured to be detachable on said extraction medium holding part of said extraction medium holding device and to be capable of transferring said extraction medium held in said extraction medium holding part to said reaction part to said extraction medium holding part of said extraction medium holding device arranged on said skin;

transferring said extraction medium held in said extraction medium holding part to said reaction part;

detecting said extract from said prescribed reaction caused in said reaction part; and

analyzing a result of detecting said extract.

2. The method of analyzing a biological component according to claim 1, wherein

said step of transferring said extraction medium to said reaction part includes a step of transferring said extraction medium through a transfer passage provided in said reaction cartridge for transferring said extraction medium to said reaction part.

3. The method of analyzing a biological component according to claim 2, wherein

said step of transferring said extraction medium to said reaction part includes a step of transferring said extraction medium held in said extraction medium holding part to said reaction part through said transfer passage by capillarity.

4. A biological component analyzer, comprising:

an extraction medium holding device having an extraction medium holding part configured to be capable of holding an extraction medium for holding an extract extracted from a subject;

a reaction cartridge including a reaction part allowing said extract to cause a prescribed reaction and a transfer passage for transferring said extraction medium held in said extraction medium holding part to said reaction part, configured to be detachable on said extraction medium holding part of said extraction medium holding device;

a detecting part detecting said extract from said prescribed reaction caused in said reaction part; and

an analysis part analyzing a result of detecting said extract.

5. The biological component analyzer according to claim 4, wherein

said transfer passage is configured to transfer said extraction medium held in said extraction medium holding part to said reaction part by capillarity.

6. The biological component analyzer according to claim 4, wherein

said transfer passage is configured to come into contact with said extraction medium held in said extraction medium holding part when said reaction cartridge is attached to said extraction medium holding part of said extraction medium holding device.

7. The biological component analyzer according to claim 4, provided with a detecting device including said detecting part and a cartridge holding part detachably holding said reaction cartridge.

8. The biological component analyzer according to claim 7, wherein

said detecting device includes said analysis part.

9. The biological component analyzer according to claim 4, further comprising transfer monitoring means monitoring that said extraction medium has been transferred from said extraction medium holding part to said reaction part.

10. The biological component analyzer according to claim 4, wherein

said extraction medium holding device includes an extraction cartridge having said extraction medium holding part and a mounting part detachably holding said extraction cartridge, detachably mounted on an extract extraction position of the subject.

11. The biological component analyzer according to claim 10, wherein

said extraction cartridge includes a liquid tank storing said extraction medium held in said extraction medium holding part, connected to said extraction medium holding part.

12. The biological component analyzer according to claim 4, wherein

said extraction medium holding device further comprises an extraction promoting part promoting extraction of said extract.

13. The biological component analyzer according to claim 4, wherein

said extract is glucose, and

said analysis part analyzes a detection result of said detecting part and acquires a blood glucose level.

14. A reaction cartridge, detachably attached to a biological component analyzer including an extraction medium holding device comprising an extraction medium holding part configured to be capable of holding an extraction medium for holding an extract extracted from a subject, comprising:

a reaction part allowing the extract to cause a prescribed reaction, and

a transfer passage so configured that one end thereof comes into contact with said extraction medium held in said extraction medium holding part and said extraction medium is transferred to said reaction part by capillarity, when attaching said reaction cartridge to said extraction medium holding device.

15. An extraction cartridge employed in a biological component analyzer analyzing an extract extracted from a subject, comprising:

an extraction medium holding part holding an extraction medium;

a liquid tank storing said extraction medium held in said extraction medium holding part, connected to said extraction medium holding part; and

an air vent provided in said extraction medium holding part for moving said extraction medium from said liquid tank to said extraction medium holding part.