DETECTION OF HYPOVOLEMIA USING IMPLANTABLE MEDICAL DEVICE

• US 20110004109A1
• Filed: 09/14/2010
• Published: 01/06/2011
• Est. Priority Date: 10/13/2005
• Status: Active Grant

• Current Assignee: Jeffrey E. Stahmann
• Original Assignee: Jeffrey E. Stahmann
• Inventors: Stahmann, Jeffrey E.
• Granted Patent: US 8,221,325 B2
• Time in Patent Office: Days
• US Class Current: 600/486
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02158 provided with two or more sensor elements
• CPC Class Codes: A61N 1/36557 controlled by chemical substances in blood
• CPC Class Codes: A61N 1/36564 controlled by blood pressure

Abstract

An implantable medical device receives a physiological signal indicative of circulatory blood volume and detects hypovolemia from that physiological signal. In one embodiment, an implantable pulmonary artery pressure (PAP) senses a PAP signal, and the implantable medical device detects hypovolemia from the PAP signal.

Claims

1. A system for monitoring a body having a pulmonary artery and a cardiac wall, the system comprising:

an hypovolemia detection module configured to receive a pulmonary artery pressure (PAP) signal via wireless telemetry, the hypovolemia detection module including a signal processor configured to process the PAP signal and a hypovolemia detector configured to produce a diastolic PAP (DPAP) using the processed PAP signal and produce at least one of a hypovolemia detection signal and a hypovolemia prediction signal using at least the DPAP, the hypovolemia detection signal indicative of a detection of hypovolemia, the hypovolemia prediction signal indicative of an elevated risk of hypovolemia.

2. The system of claim 1, wherein the hypovolemia detector is configured to produce a systolic PAP (SPAP) using the processed PAP signal and produce the at least one of the hypovolemia detection signal and the hypovolemia prediction signal using the DPAP and the SPAP.

3. The system of claim 2, wherein the hypovolemia detector is configured to produce a mean PAP (MPAP) using the DPAP and SPAP and produce the at least one of the hypovolemia detection signal and the hypovolemia prediction signal using the MPAP.

4. The system of claim 1, comprising an implantable pulmonary artery pressure (PAP) sensor configured to be placed in the body to sense the PAP signal.

5. The system of claim 4, comprising an anchoring structure coupled to the implantable PAP sensor and configured to anchor the implantable PAP sensor within the pulmonary artery.

6. The system of claim 4, comprising an anchoring structure coupled to the implantable PAP sensor and configured to anchor the implantable PAP sensor to the cardiac wall.

7. The system of claim 1, comprising an implantable medical device including the hypovolemia detection module, and the hypovolemia detection module is configured to be communicatively coupled to the implantable PAP sensor via an ultrasonic telemetry link.

8. The system of claim 7, wherein the implantable medical device further comprises an edema detection module adapted to detect an edema and produce a detection signal indicative of a detection of the edema.

9. The system of claim 8, wherein the hypovolemia detector is configured to produce at least the hypovolemia detection signal, and the implantable medical device further comprises:

a therapy delivery device adapted to deliver one or more therapies; and

a therapy controller adapted to control the delivery of the one or more therapies using at least the hypovolemia detection signal and the edema detection signal.

10. A method for monitoring a patient, the method comprising:

receiving a pulmonary artery pressure (PAP) signal from an implantable PAP sensor via wireless telemetry;

producing a diastolic PAP (DPAP) using the PAP signal; and

producing at least one of a hypovolemia detection signal and a hypovolemia prediction signal using at least the DPAP, the hypovolemia detection signal indicative of a detection of hypovolemia, the hypovolemia prediction signal indicative of an elevated risk of hypovolemia.

11. The method of claim 10, further comprising:

producing a systolic PAP (SPAP) using the PAP signal; and

producing the at least one of the hypovolemia detection signal and the hypovolemia prediction signal using the DPAP and the SPAP.

12. The method of claim 11, further comprising:

calculating a mean PAP (MPAP) using the DPAP and the SPAP; and

producing the at least one of the hypovolemia detection signal and the hypovolemia prediction signal using the MPAP.

13. The method of claim 10, comprising placing the implantable PAP sensor within a pulmonary artery.

14. The method of claim 10, comprising anchoring the implantable PAP sensor to a cardiac wall.

15. The method of claim 10, further comprising:

sensing a physiological signal indicative of a fluid retention;

detecting an edema from the physiological signal; and

producing an edema detection signal when the edema is detected.

16. The method of claim 15, wherein producing the at least one of the hypovolemia detection signal and the hypovolemia prediction signal comprises producing at least the hypovolemia detection signal, and further comprising:

delivering one or more therapies; and

controlling the delivery of the one or more therapies using the hypovolemia detection signal and the edema detection signal.

17. A system configured to be coupled to a body having a pulmonary artery, comprising:

means for receiving a pulmonary artery pressure (PAP) signal;

means for producing a diastolic PAP (DPAP) using the PAP signal; and

means for producing at least one of a hypovolemia detection signal and a hypovolemia prediction signal using at least the DPAP, the hypovolemia detection signal indicative of a detection of hypovolemia, the hypovolemia prediction signal indicative of an elevated risk of hypovolemia.

18. The system of claim 17, comprising implantable means for sensing the PAP.

19. The system of claim 18, wherein the implantable means for sensing the PAP comprises a pressure sensor and means for anchoring the pressure sensor within the pulmonary artery.

20. The system of claim 18, wherein the implantable means for sensing the PAP comprises a pressure sensor and means for anchoring the pressure sensor in the body outside the pulmonary artery.