METHODS FOR MANUFACTURING MICROPROJECTION ARRAYS
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Accused Products
Abstract
Methods for the manufacture of a microprojection array are provided. In the methods, a formulation is introduced into cavities of a microprojection array mold by means that achieve a uniform amount of formulation retained in each cavity.
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Citations
54 Claims
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1-17. -17. (canceled)
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20-28. -28. (canceled)
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29. A method of forming a microprojection array, comprising:
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dispensing a quantity of a formulation on a substrate, contacting a mold having a plurality of cavities for individual microprojections in the array with the formulation dispensed on the substrate, wherein the mold and the formulation are contacted such that the plurality of cavities are in fluid communication with the formulation, transferring formulation into the plurality of cavities; and disengaging the mold from the formulation and the substrate in a manner that retains formulation in each of the plurality of cavities. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46)
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47. A method of fabricating a microprojection array, comprising:
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positioning a mold comprising a plurality of cavities for forming microprojections in an array of microprojections in a fixture, the fixture comprised of a first member and a second member and at least one port, the mold positioned between the first and second members; introducing a formulation into the fixture through the at least one port such that the formulation contacts openings to the plurality of cavities in the mold; transferring the formulation introduced into the fixture into the plurality of cavities; and withdrawing formulation from the fixture at a rate whereby formulation transferred into the plurality of cavities is retained in each cavity in the plurality. - View Dependent Claims (48, 49, 50, 51, 52, 53, 54)
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Specification