Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
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Accused Products
Abstract
Macro- and microfluidic devices and related technologies, and chemical processes using such devices. More specifically, the devices may be used for a fully automated synthesis of radioactive compounds for imaging, such as by positron emission tomography (PET), in an efficient, compact and safe to the operator manner. In particular, embodiments of the present invention relate to an automated, multi-run, microfluidic instrument for the multi-step synthesis of radiopharmaceuticals, such as PET probes, comprising a remote shielded mini-cell containing radiation-handing components.
67 Citations
65 Claims
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1-20. -20. (canceled)
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21. An instrument for synthesis of radiolabeled compounds comprising:
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one or more “
hot”
component units; andat least one “
cold”
component unit;wherein the one or more “
hot”
component units and the at least one “
cold”
component unit are separate units that are operatively connected to each other, and the one or more “
hot”
component units and the at least one “
cold”
component unit being positioned from each other to reduce radiation exposure to a user and sensitive equipment. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65)
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Specification