RENAL THERAPY SYSTEM HAVING PUMP REVERSING FLUID CONTROL

• US 20110009798A1
• Filed: 09/17/2010
• Published: 01/13/2011
• Est. Priority Date: 11/05/2003
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Childers, Robert W., Din, Shahid, El Sayyid, Waleed Mutasem, Kelly, Thomas, Busby, Don, Roger, Rodolfo
• Granted Patent: US 9,072,843 B2
• Time in Patent Office: Days
• US Class Current: 604/6.09
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/153 the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/15625 the reservoirs acting as balance chambers
• CPC Class Codes: A61M 1/1563 Details of incorporated filters
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1601 Control or regulation
• CPC Class Codes: A61M 1/1607 before use, i.e. upstream of dialyser
• CPC Class Codes: A61M 1/1613 Profiling or modelling of patient or predicted treatment evolution or outcome
• CPC Class Codes: A61M 1/1621 Constructional aspects thereof semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi permeable membranes characterised by their material B01D71/00
• CPC Class Codes: A61M 1/1629 with integral heat exchanger
• CPC Class Codes: A61M 1/1633 with more than one dialyser unit
• CPC Class Codes: A61M 1/1635 with volume chamber balancing devices between used and fresh dialysis fluid
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/1668 Details of containers
• CPC Class Codes: A61M 1/167 Flexible packaging for solid concentrates
• CPC Class Codes: A61M 1/1672 : using membrane filters, e.g. for sterilising the dialysate
• CPC Class Codes: A61M 1/1696 : with dialysate regeneration
• CPC Class Codes: A61M 1/267 : used for pumping
• CPC Class Codes: A61M 1/288 : Priming priming in extracorporeal blood circuits A61M1/3643
• CPC Class Codes: A61M 1/3401 : Cassettes therefor
• CPC Class Codes: A61M 1/341 : by measuring the filtrate rate or volume
• CPC Class Codes: A61M 1/3417 : using distinct filters for dialysis and ultra-filtration
• CPC Class Codes: A61M 1/342 : Adding solutions to the blood, e.g. substitution solutions for preventing coagulation A61M1/3672
• CPC Class Codes: A61M 1/3427 : back through the membrane, e.g. by inverted trans-membrane pressure [TMP]
• CPC Class Codes: A61M 1/3431 : upstream of the filter
• CPC Class Codes: A61M 1/3434 : with pre-dilution and post-dilution
• CPC Class Codes: A61M 1/3437 : downstream of the filter, e.g. post-dilution with filtrate
• CPC Class Codes: A61M 1/3444 : in which the collected ultra-filtrate expels an equal volume of substitution fluid from a reservoir
• CPC Class Codes: A61M 1/3451 : the difference in weight between both ultra-filtrate and substitution reservoir being used as control signal
• CPC Class Codes: A61M 1/3458 : having electrolytes not present in the dialysate
• CPC Class Codes: A61M 1/3465 : using dialysate as substitution fluid
• CPC Class Codes: A61M 1/3468 : using treated filtrate as substitution fluid
• CPC Class Codes: A61M 1/3472 : with treatment of the filtrate
• CPC Class Codes: A61M 1/3486 : Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
• CPC Class Codes: A61M 1/3621 : Extra-corporeal blood circuits single-needle circuits A61M1/30
• CPC Class Codes: A61M 1/362223 : the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/36224 : with sensing means or components thereof
• CPC Class Codes: A61M 1/36225 : with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362261 : at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362265 : Details of valves
• CPC Class Codes: A61M 1/3624 : Level detectors; Level control
• CPC Class Codes: A61M 1/3626 : Gas bubble detectors
• CPC Class Codes: A61M 1/3627 : Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
• CPC Class Codes: A61M 1/3643 : Priming, rinsing before or after use
• CPC Class Codes: A61M 1/3644 : Mode of operation
• CPC Class Codes: A61M 1/3646 : Expelling the residual body fluid after use, e.g. back to the body
• CPC Class Codes: A61M 1/3647 : with recirculation of the priming solution
• CPC Class Codes: A61M 1/3649 : using dialysate as priming or rinsing liquid
• CPC Class Codes: A61M 1/365 : through membranes, e.g. by inverted trans-membrane pressure [TMP]
• CPC Class Codes: A61M 1/3652 : using gas, e.g. air
• CPC Class Codes: A61M 1/3656 : Monitoring patency or flow at connection sites; Detecting disconnections
• CPC Class Codes: A61M 2202/0413 : Blood
• CPC Class Codes: A61M 2205/12 : with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/127 : with provisions for heating or cooling
• CPC Class Codes: A61M 2205/13 : with means for the detection of operative contact with patient, e.g. lip sensor
• CPC Class Codes: A61M 2205/15 : Detection of leaks
• CPC Class Codes: A61M 2205/18 : with alarm
• CPC Class Codes: A61M 2205/276 : preventing unwanted use
• CPC Class Codes: A61M 2205/3317 : Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 : PH measuring means
• CPC Class Codes: A61M 2205/3327 : Measuring
• CPC Class Codes: A61M 2205/3331 : Pressure; Flow
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3337 : Controlling, regulating pressure or flow by means of a valve by-passing a pump
• CPC Class Codes: A61M 2205/3344 : Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2205/3368 : Temperature
• CPC Class Codes: A61M 2205/3379 : Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 2205/3393 : by weighing the reservoir
• CPC Class Codes: A61M 2205/3553 : remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3561 : local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3584 : using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/502 : User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/505 : Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
• CPC Class Codes: A61M 2205/52 : with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/75 : with filters
• CPC Class Codes: A61M 60/113 : in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/258 : Piston pumps
• CPC Class Codes: A61M 60/279 : Peristaltic pumps, e.g. roller pumps
• CPC Class Codes: A61M 60/37 : Haemodialysis, haemofiltration or diafiltration
• CPC Class Codes: A61M 60/43 : using vacuum at the blood pump, e.g. to accelerate filling
• CPC Class Codes: A61M 60/508 : Electronic control means, e.g. for feedback regulation
• CPC Class Codes: A61M 60/847 : arranged in a cassette
• CPC Class Codes: A61M 60/849 : Disposable parts
• CPC Class Codes: A61M 60/851 : Valves

Abstract

A renal therapy system includes: a filter; an arterial blood flowpath in fluid communication with the filter; a venous blood flowpath in fluid communication with the filter; extracorporeal circuit including the filter, the arterial blood flowpath and the venous blood flowpath; a renal therapy fluid flowpath in fluid communication with the extracorporeal circuit; a plurality of renal therapy fluid valves; and first and second renal therapy fluid pumps, wherein the system is configured to operate the plurality of renal therapy fluid valves so that (i) the first renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath to the extracorporeal circuit for a number of first pump actuations and (ii) the second renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath for a number of second pump actuations.

Claims

1. A renal therapy system comprising:

a filter;

an arterial blood flowpath in fluid communication with the filter;

a venous blood flowpath in fluid communication with the filter;

extracorporeal circuit including the filter, the arterial blood flowpath and the venous blood flowpath;

a renal therapy fluid flowpath in fluid communication with the extracorporeal circuit;

a plurality of renal therapy fluid valves; and

first and second renal therapy fluid pumps, wherein the system is configured to operate the plurality of renal therapy fluid valves so that (i) the first renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath to the extracorporeal circuit for a number of first pump actuations and (ii) the second renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath for a number of second pump actuations.

2. The renal therapy system of claim 1, wherein the number of first pump actuations equals the number of second pump actuations.

3. The renal therapy system of claim 1, which is a hemofiltration system, the filter a hemofilter, the renal therapy fluid a replacement fluid, and the renal therapy fluid flowpath connected fluidly to one of the arterial and venous blood flowpaths.

4. The hemofiltration system of claim 3, wherein the renal therapy fluid flowpath is a first flowpath, and which includes a second renal therapy fluid flowpath connected fluidly to the hemofilter, the hemofiltration system further configured to operate the plurality of renal therapy fluid valves so that during (i), the second renal therapy fluid pump pulls effluent from the hemofilter through the second renal therapy fluid flowpath and during (ii), the first renal therapy fluid pump pulls effluent from the hemofilter through the second renal therapy fluid flowpath.

5. The hemofiltration system of claim 4, wherein the second renal therapy fluid pump pulls for a number of actuations equal to a number of pulling actuations of the first renal therapy fluid pump.

6. The hemofiltration system of claim 4, wherein at least one of the first and second renal therapy fluid pumps pulls for a number of actuations equal to at least one of the number of first pump actuations and the number of second pump actuations.

7. The renal therapy system of claim 1, which is a hemodialysis system, the filter a dialyzer. the renal therapy fluid a dialysate, and the renal therapy fluid flowpath connected fluidly to the dialyzer.

8. The hemodialysis system of claim 7, wherein the renal therapy fluid flowpath is a first flowpath, and which includes a second renal therapy flowpath connected fluidly to the dialyzer, the hemodialysis system further configured to operate the renal fluid therapy valves so that during (i), the second renal therapy fluid pump pulls effluent from the dialyzer through the second renal therapy fluid flowpath and during (ii), the first renal therapy fluid pump pulls effluent from the dialyzer through the second renal therapy fluid flowpath.

9. The hemodialysis system of claim 8, wherein the second renal therapy fluid pump pulls for a number of actuations equal to a number of pulling actuations of the first renal therapy fluid pump.

10. The hemodialysis system of claim 8, wherein at least one of the first and second renal therapy fluid pumps pulls for a number of actuations equal to at least one of the number of first pump actuations and the number of second pump actuations.

11. The renal therapy system of claim 1, which includes a fluid cassette operable with a machine of the system, at least one of (i) a portion of the arterial blood flowpath, (ii) a portion of the venous blood flowpath, (iii) at least a portion of the renal fluid therapy flowpath, (iv) at least one valve area operable with at least one of the renal therapy fluid valves, and (v) at least one pump area operable with at least one of the first and second renal therapy fluid pumps is provided by the fluid cassette.

12. A renal therapy system comprising:

a dialyzer;

an arterial blood flowpath in fluid communication with the dialyzer;

a venous blood flowpath in fluid communication with the dialyzer;

a first dialysate flowpath in fluid communication with the dialyzer;

a second dialysate flowpath in fluid communication with the dialyzer;

a plurality of dialysate valves; and

first and second dialysate pumps, wherein the system is configured to operate the plurality of dialysate valves so that (i) the first dialysate pump pumps dialysate through one of the first and second dialysate flowpaths to the dialyzer for a number of first pump actuations and (ii) the second dialysate pump pumps dialysate through one of the first and second dialysate flowpaths to the dialyzer for a number of second pump actuations.

13. The renal therapy system of claim 12, wherein the number of first pump actuations equals the number of second pump actuations.

14. The renal therapy system of claim 12, which includes a fluid cassette operable with a machine of the system, at least one of (i) a portion of the arterial blood flowpath, (ii) a portion of the venous blood flowpath, (iii) a portion of the first dialysate flowpath, (iv) a portion of the second dialysate flowpath;

(v) at least one valve area operable with at least one of the dialysate valves, and (vi) at least one pump area operable with at least one of the first and second dialysate pumps is provided by the fluid cassette.

15. The renal therapy system of claim 12, which is further configured so that during (i), the second dialysate pump pulls effluent from the dialyzer through the other of the first and second dialysate flowpaths and during (ii), the first dialysate pump pulls effluent from the dialyzer through the other of the first and second dialysate flowpaths.

16. The renal therapy system of claim 15, wherein the second renal therapy fluid pump pulls for a number of actuations equal to a number of pulling actuations of the first renal therapy fluid pump.

17. The renal therapy system of claim 15, wherein at least one of the first and second renal therapy fluid pumps pulls for a number of actuations equal to at least one of the number of first pump actuations and the number of second pump actuations.

18. The renal therapy system of claim 12, wherein the plurality, of valves includes first and second valves respectively enabling a dialysate supply to communicate fluidly with the first and second dialysate pumps.

19. The renal therapy system of claim 12, wherein. during (i) and (ii) both first and second dialysate pumps pump through the same one of the first and second dialysate flowpaths to the dialyzer.

20. A renal therapy system comprising:

a filter;

an arterial blood flowpath in fluid communication with the filter;

a venous blood flowpath in fluid communication with the filter;

first and second renal therapy fluid pumps;

a renal therapy fluid supply; and

first and second renal therapy fluid valves, the system configured to operate such that (i) thefirst renal therapy fluid valve allows the first renal therapy fluid pump to pump renal therapy fluid from the renal therapy fluid supply to the filter for a number of first pump actuations and (ii) the second renal therapy fluid valve allows the second renal therapy fluid pump to pump renal therapy fluid from the renal therapy fluid supply to the filter for a number of second pump actuations.

21. The renal therapy system of claim 20, wherein the number of first pump actuations equals the number of second pump actuations.

22. The renal therapy system of claim 20, which includes a renal therapy fluid line in fluid communication with the filter and third and fourth fluid valves operated to selectively allow the first or second renal therapy fluid pump to pump renal therapy fluid through the renal therapy fluid line to the filter.

23. The renal therapy system of claim 20, wherein at least one of:

during (i), the second renal therapy fluid pump pulls effluent from the filter and during (ii), the first renal therapy fluid pump pulls effluent from the filter.