METHODS FOR OBTAINING ADULT HUMAN OLFACTORY PROGENITOR CELLS
First Claim
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1. A primary culture, or a subculture thereof, of human olfactory neuroepithelium (ONe)-sourced cells comprising cells that are, individually, immunoreactive for both nestin and beta-tubulin isotype III.
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Abstract
An isolated human olfactory stem cell can be prepared by culturing human tissue from olfactory neuroepithelium to form neurospheres.
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23 Claims
- 1. A primary culture, or a subculture thereof, of human olfactory neuroepithelium (ONe)-sourced cells comprising cells that are, individually, immunoreactive for both nestin and beta-tubulin isotype III.
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18. A primary culture, or a subculture thereof, of human olfactory neuroepithelium (ONe)-sourced cells comprising neurospheres, wherein the neurospheres comprise cells that are, individually, immunoreactive for both nestin and beta-tubulin isotype III.
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19. Neurospheres derived from numan olfactory neuroepithelium (ONe), wherein the neurospheres comprise cells that are, individually, immunoreactive for both nestin and beta-tubulin isotype III, or progeny of the cells that are, individually, immunoreactive for both nestin and beta-tubulin isotype III, wherein the progeny of the cells are capable of forming neurospheres.
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20. A kit, comprising:
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a plurality of human ONe-sourced cells that are, individually, immunoreactive for both nestin and beta-tubulin isotype III; and instructional material, wherein the instructional material comprises text that indicates that the plurality of human ONe-sourced cells are, individually, immunoreactive for both nestin and beta-tubulin isotype III. - View Dependent Claims (21, 22, 23)
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Specification