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ARACHNOCAMPA LUCIFERASES

  • US 20110015095A1
  • Filed: 08/18/2006
  • Published: 01/20/2011
  • Est. Priority Date: 08/19/2005
  • Status: Active Grant
First Claim
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1. An isolated peptide that displays luciferase activity, whereina. the luciferase activity comprises catalysis of a luminescence reaction dependent upon ATP;

  • andb. the luminescence reaction produces an emission spectrum with a maximum emission intensity at wavelengths less than or equal to 530±

    5 nm; and

    c. the peptide has an amino acid sequence that, when aligned with that of SEQ ID NO;

    4, differs from that of SEQ ID NO;

    4 by at least one change in amino acid sequence selected from the group consisting of deletion of R218, H245N, G315S, L342S, and T343S.

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